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Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids.
Wu J, Zhang J, Chen X, Wettschurack K, Que Z, Deming BA, Olivero-Acosta MI, Cui N, Eaton M, Zhao Y, Li SM, Suzuki M, Chen I, Xiao T, Halurkar MS, Mandal P, Yuan C, Xu R, Koss WA, Du D, Chen F, Wu LJ, Yang Y. Wu J, et al. Among authors: xu r. Mol Psychiatry. 2024 Aug;29(8):2424-2437. doi: 10.1038/s41380-024-02518-4. Epub 2024 Mar 18. Mol Psychiatry. 2024. PMID: 38499656
Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism.
Wang L, Mirabella VR, Dai R, Su X, Xu R, Jadali A, Bernabucci M, Singh I, Chen Y, Tian J, Jiang P, Kwan KY, Pak C, Liu C, Comoletti D, Hart RP, Chen C, Südhof TC, Pang ZP. Wang L, et al. Among authors: xu r. Mol Psychiatry. 2024 Jun;29(6):1620-1635. doi: 10.1038/s41380-022-01834-x. Epub 2022 Oct 24. Mol Psychiatry. 2024. PMID: 36280753 Free PMC article.
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids.
Yang Y, Wu J, Zhang J, Chen X, Que Z, Wettschurack K, Deming B, Acosta M, Cui N, Eaton M, Zhao Y, Halurkar M, Purba M, Chen I, Xiao T, Suzuki M, Yuan C, Xu R, Koss W, Du D, Chen F, Wu LJ, Clinic M. Yang Y, et al. Among authors: xu r. Res Sq [Preprint]. 2023 Sep 28:rs.3.rs-3270664. doi: 10.21203/rs.3.rs-3270664/v1. Res Sq. 2023. Update in: Mol Psychiatry. 2024 Aug;29(8):2424-2437. doi: 10.1038/s41380-024-02518-4 PMID: 37841865 Free PMC article. Updated. Preprint.
Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated SCN2A-L1342P mutation.
Que Z, Olivero-Acosta MI, Chen I, Zhang J, Wettschurack K, Wu J, Xiao T, Otterbacher CM, Wang M, Harlow H, Cui N, Chen X, Deming B, Halurkar M, Zhao Y, Rochet JC, Xu R, Brewster AL, Wu LJ, Yuan C, Skarnes WC, Yang Y. Que Z, et al. Among authors: xu r. bioRxiv [Preprint]. 2023 Oct 31:2023.10.26.563426. doi: 10.1101/2023.10.26.563426. bioRxiv. 2023. Update in: J Neurosci. 2024 Nov 18:e2027232024. doi: 10.1523/JNEUROSCI.2027-23.2024 PMID: 37961213 Free PMC article. Updated. Preprint.
Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated SCN2A-L1342P mutation.
Que Z, Olivero-Acosta MI, Robinson M, Chen I, Zhang J, Wettschurack K, Wu J, Xiao T, Otterbacher CM, Shankar V, Harlow H, Hong S, Zirkle B, Wang M, Cui N, Mandal P, Chen X, Deming B, Halurkar M, Zhao Y, Rochet JC, Xu R, Brewster AL, Wu LJ, Yuan C, Skarnes WC, Yang Y. Que Z, et al. Among authors: xu r. J Neurosci. 2024 Nov 18:e2027232024. doi: 10.1523/JNEUROSCI.2027-23.2024. Online ahead of print. J Neurosci. 2024. PMID: 39557580
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