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Page 1
Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses.
Trifinopoulos J, List J, Klampfl T, Klein K, Prchal-Murphy M, Witalisz-Siepracka A, Bellutti F, Fava LL, Heller G, Stummer S, Testori P, Den Boer ML, Boer JM, Marinovic S, Hoermann G, Walter W, Villunger A, Sicinski P, Sexl V, Gotthardt D. Trifinopoulos J, et al. Among authors: klampfl t. Haematologica. 2024 Oct 10. doi: 10.3324/haematol.2024.285701. Online ahead of print. Haematologica. 2024. PMID: 39385738 Free article.
Kinase-inactivated CDK6 preserves the long-term functionality of adult hematopoietic stem cells.
Mayer IM, Doma E, Klampfl T, Prchal-Murphy M, Kollmann S, Schirripa A, Scheiblecker L, Zojer M, Kunowska N, Gebrail L, Shaw LE, Mann U, Farr A, Grausenburger R, Heller G, Zebedin-Brandl E, Farlik M, Malumbres M, Sexl V, Kollmann K. Mayer IM, et al. Among authors: klampfl t. Blood. 2024 Jul 11;144(2):156-170. doi: 10.1182/blood.2023021985. Blood. 2024. PMID: 38684032 Free PMC article.
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia.
Klein K, Kollmann S, Hiesinger A, List J, Kendler J, Klampfl T, Rhandawa M, Trifinopoulos J, Maurer B, Grausenburger R, Betram CA, Moriggl R, Rülicke T, Mullighan CG, Witalisz-Siepracka A, Walter W, Hoermann G, Sexl V, Gotthardt D. Klein K, et al. Among authors: klampfl t. Blood. 2024 Jun 13;143(24):2474-2489. doi: 10.1182/blood.2023022655. Blood. 2024. PMID: 38498036 Free PMC article.
SBNO2 is a critical mediator of STAT3-driven hematological malignancies.
Brandstoetter T, Schmoellerl J, Grausenburger R, Kollmann S, Doma E, Huuhtanen J, Klampfl T, Eder T, Grebien F, Hoermann G, Zuber J, Mustjoki S, Maurer B, Sexl V. Brandstoetter T, et al. Among authors: klampfl t. Blood. 2023 Apr 13;141(15):1831-1845. doi: 10.1182/blood.2022018494. Blood. 2023. PMID: 36630607 Free PMC article.
CDK6 Degradation Is Counteracted by p16INK4A and p18INK4C in AML.
Schmalzbauer BS, Thondanpallil T, Heller G, Schirripa A, Sperl CM, Mayer IM, Knab VM, Nebenfuehr S, Zojer M, Mueller AC, Fontaine F, Klampfl T, Sexl V, Kollmann K. Schmalzbauer BS, et al. Among authors: klampfl t. Cancers (Basel). 2022 Mar 18;14(6):1554. doi: 10.3390/cancers14061554. Cancers (Basel). 2022. PMID: 35326705 Free PMC article.
A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells.
Kollmann S, Grausenburger R, Klampfl T, Prchal-Murphy M, Bastl K, Pisa H, Knab VM, Brandstoetter T, Doma E, Sperr WR, Lagger S, Farlik M, Moriggl R, Valent P, Halbritter F, Kollmann K, Heller G, Maurer B, Sexl V. Kollmann S, et al. Among authors: klampfl t. Blood. 2021 Dec 9;138(23):2347-2359. doi: 10.1182/blood.2021010980. Blood. 2021. PMID: 34320169 Free PMC article.
Mutant Calreticulin in the Myeloproliferative Neoplasms.
Prins D, González Arias C, Klampfl T, Grinfeld J, Green AR. Prins D, et al. Among authors: klampfl t. Hemasphere. 2020 Jan 15;4(1):e333. doi: 10.1097/HS9.0000000000000333. eCollection 2020 Feb. Hemasphere. 2020. PMID: 32382708 Free PMC article. Review.
Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage.
Li J, Prins D, Park HJ, Grinfeld J, Gonzalez-Arias C, Loughran S, Dovey OM, Klampfl T, Bennett C, Hamilton TL, Pask DC, Sneade R, Williams M, Aungier J, Ghevaert C, Vassiliou GS, Kent DG, Green AR. Li J, et al. Among authors: klampfl t. Blood. 2018 Feb 8;131(6):649-661. doi: 10.1182/blood-2017-09-806356. Epub 2017 Dec 27. Blood. 2018. PMID: 29282219 Free article.
Germline RBBP6 mutations in familial myeloproliferative neoplasms.
Harutyunyan AS, Giambruno R, Krendl C, Stukalov A, Klampfl T, Berg T, Chen D, Milosevic Feenstra JD, Jäger R, Gisslinger B, Gisslinger H, Rumi E, Passamonti F, Pietra D, Müller AC, Parapatics K, Breitwieser FP, Herrmann R, Colinge J, Bennett KL, Superti-Furga G, Cazzola M, Hammond E, Kralovics R. Harutyunyan AS, et al. Among authors: klampfl t. Blood. 2016 Jan 21;127(3):362-5. doi: 10.1182/blood-2015-09-668673. Epub 2015 Nov 16. Blood. 2016. PMID: 26574608 Free PMC article. No abstract available.
26 results