Lloyd RS - Search Results

1

Mass Spectrometry-Based Method to Measure Aflatoxin B₁ DNA Adducts in Formalin-Fixed Paraffin-Embedded Tissues.

Bellamri M, Yao L, Tomar R, Vartanian V, Rizzo CJ, Stone MP, Groopman JD, Lloyd RS, Turesky RJ. Bellamri M, et al. Among authors: lloyd rs. Chem Res Toxicol. 2024 Apr 15;37(4):633-642. doi: 10.1021/acs.chemrestox.4c00005. Epub 2024 Mar 18. Chem Res Toxicol. 2024. PMID: 38498000

2

Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.

Minko IG, Kozekov ID, Harris TM, Rizzo CJ, Lloyd RS, Stone MP. Minko IG, et al. Among authors: lloyd rs. Chem Res Toxicol. 2009 May;22(5):759-78. doi: 10.1021/tx9000489. Chem Res Toxicol. 2009. PMID: 19397281 Free PMC article. Review.

3

Aflatoxin-Guanine DNA Adducts and Oxidatively Induced DNA Damage in Aflatoxin-Treated Mice in Vivo as Measured by Liquid Chromatography-Tandem Mass Spectrometry with Isotope Dilution.

Coskun E, Jaruga P, Vartanian V, Erdem O, Egner PA, Groopman JD, Lloyd RS, Dizdaroglu M. Coskun E, et al. Among authors: lloyd rs. Chem Res Toxicol. 2019 Jan 22;32(1):80-89. doi: 10.1021/acs.chemrestox.8b00202. Epub 2018 Dec 19. Chem Res Toxicol. 2019. PMID: 30525498 Free PMC article.

4

DNA Sequence Modulates the Efficiency of NEIL1-Catalyzed Excision of the Aflatoxin B₁-Induced Formamidopyrimidine Guanine Adduct.

Tomar R, Minko IG, Kellum AH Jr, Voehler MW, Stone MP, McCullough AK, Lloyd RS. Tomar R, et al. Among authors: lloyd rs. Chem Res Toxicol. 2021 Mar 15;34(3):901-911. doi: 10.1021/acs.chemrestox.0c00517. Epub 2021 Feb 17. Chem Res Toxicol. 2021. PMID: 33595290 Free PMC article.

5

Structure of a site specific major groove (2S,3S)-N6-(2,3,4-trihydroxybutyl)-2'-deoxyadenosyl DNA adduct of butadiene diol epoxide.

Scholdberg TA, Nechev LV, Merritt WK, Harris TM, Harris CM, Lloyd RS, Stone MP. Scholdberg TA, et al. Among authors: lloyd rs. Chem Res Toxicol. 2004 Jun;17(6):717-30. doi: 10.1021/tx034271+. Chem Res Toxicol. 2004. PMID: 15206893

6

Stereospecific structural perturbations arising from adenine N(6) butadiene triol adducts in duplex DNA.

Merritt WK, Scholdberg TA, Nechev LV, Harris TM, Harris CM, Lloyd RS, Stone MP. Merritt WK, et al. Among authors: lloyd rs. Chem Res Toxicol. 2004 Aug;17(8):1007-19. doi: 10.1021/tx049908j. Chem Res Toxicol. 2004. PMID: 15310233

7

Mispairing of a site specific major groove (2S,3S)-N6-(2,3,4-trihydroxybutyl)-2'-deoxyadenosyl DNA Adduct of butadiene diol epoxide with deoxyguanosine: formation of a dA(anti).dG(anti) pairing interaction.

Scholdberg TA, Nechev LV, Merritt WK, Harris TM, Harris CM, Lloyd RS, Stone MP. Scholdberg TA, et al. Among authors: lloyd rs. Chem Res Toxicol. 2005 Feb;18(2):145-53. doi: 10.1021/tx049772p. Chem Res Toxicol. 2005. PMID: 15720118

8

Dual roles of glycosyl torsion angle conformation and stereochemical configuration in butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adducts: a structural perspective.

Merritt WK, Kowalczyk A, Scholdberg TA, Dean SM, Harris TM, Harris CM, Lloyd RS, Stone MP. Merritt WK, et al. Among authors: lloyd rs. Chem Res Toxicol. 2005 Jul;18(7):1098-107. doi: 10.1021/tx050023x. Chem Res Toxicol. 2005. PMID: 16022502 Free PMC article.

9

Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequence.

Cho YJ, Wang H, Kozekov ID, Kurtz AJ, Jacob J, Voehler M, Smith J, Harris TM, Lloyd RS, Rizzo CJ, Stone MP. Cho YJ, et al. Among authors: lloyd rs. Chem Res Toxicol. 2006 Feb;19(2):195-208. doi: 10.1021/tx050239z. Chem Res Toxicol. 2006. PMID: 16485895 Free PMC article.

10

Orientation of the crotonaldehyde-derived N2-[3-Oxo-1(S)-methyl-propyl]-dG DNA adduct hinders interstrand cross-link formation in the 5'-CpG-3' sequence.

Cho YJ, Wang H, Kozekov ID, Kozekova A, Kurtz AJ, Jacob J, Voehler M, Smith J, Harris TM, Rizzo CJ, Lloyd RS, Stone MP. Cho YJ, et al. Among authors: lloyd rs. Chem Res Toxicol. 2006 Aug;19(8):1019-29. doi: 10.1021/tx0600604. Chem Res Toxicol. 2006. PMID: 16918240

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