Chen K - Search Results

1

Coactivator condensation drives cardiovascular cell lineage specification.

Gan P, Eppert M, De La Cruz N, Lyons H, Shah AM, Veettil RT, Chen K, Pradhan P, Bezprozvannaya S, Xu L, Liu N, Olson EN, Sabari BR. Gan P, et al. Among authors: chen k. Sci Adv. 2024 Mar 15;10(11):eadk7160. doi: 10.1126/sciadv.adk7160. Epub 2024 Mar 15. Sci Adv. 2024. PMID: 38489358 Free PMC article.

2

Twist2 amplification in rhabdomyosarcoma represses myogenesis and promotes oncogenesis by redirecting MyoD DNA binding.

Li S, Chen K, Zhang Y, Barnes SD, Jaichander P, Zheng Y, Hassan M, Malladi VS, Skapek SX, Xu L, Bassel-Duby R, Olson EN, Liu N. Li S, et al. Among authors: chen k. Genes Dev. 2019 Jun 1;33(11-12):626-640. doi: 10.1101/gad.324467.119. Epub 2019 Apr 11. Genes Dev. 2019. PMID: 30975722 Free PMC article.

3

Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing.

Cui M, Wang Z, Chen K, Shah AM, Tan W, Duan L, Sanchez-Ortiz E, Li H, Xu L, Liu N, Bassel-Duby R, Olson EN. Cui M, et al. Among authors: chen k. Dev Cell. 2020 Apr 6;53(1):102-116.e8. doi: 10.1016/j.devcel.2020.02.019. Epub 2020 Mar 26. Dev Cell. 2020. PMID: 32220304 Free PMC article.

4

Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing.

Cui M, Wang Z, Chen K, Shah AM, Tan W, Duan L, Sanchez-Ortiz E, Li H, Xu L, Liu N, Bassel-Duby R, Olson EN. Cui M, et al. Among authors: chen k. Dev Cell. 2020 Dec 7;55(5):665-667. doi: 10.1016/j.devcel.2020.11.006. Dev Cell. 2020. PMID: 33290696 Free PMC article. No abstract available.

5

The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization.

Ramirez-Martinez A, Zhang Y, Chen K, Kim J, Cenik BK, McAnally JR, Cai C, Shelton JM, Huang J, Brennan A, Evers BM, Mammen PPA, Xu L, Bassel-Duby R, Liu N, Olson EN. Ramirez-Martinez A, et al. Among authors: chen k. Nat Commun. 2021 Jan 29;12(1):690. doi: 10.1038/s41467-021-20987-x. Nat Commun. 2021. PMID: 33514739 Free PMC article.

6

The histone reader PHF7 cooperates with the SWI/SNF complex at cardiac super enhancers to promote direct reprogramming.

Garry GA, Bezprozvannaya S, Chen K, Zhou H, Hashimoto H, Morales MG, Liu N, Bassel-Duby R, Olson EN. Garry GA, et al. Among authors: chen k. Nat Cell Biol. 2021 May;23(5):467-475. doi: 10.1038/s41556-021-00668-z. Epub 2021 May 3. Nat Cell Biol. 2021. PMID: 33941892 Free PMC article.

7

Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance.

Cui M, Atmanli A, Morales MG, Tan W, Chen K, Xiao X, Xu L, Liu N, Bassel-Duby R, Olson EN. Cui M, et al. Among authors: chen k. Nat Commun. 2021 Sep 6;12(1):5270. doi: 10.1038/s41467-021-25653-w. Nat Commun. 2021. PMID: 34489413 Free PMC article.

8

Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy.

Nishiyama T, Zhang Y, Cui M, Li H, Sanchez-Ortiz E, McAnally JR, Tan W, Kim J, Chen K, Xu L, Bassel-Duby R, Olson EN. Nishiyama T, et al. Among authors: chen k. Sci Transl Med. 2022 Nov 23;14(672):eade1633. doi: 10.1126/scitranslmed.ade1633. Epub 2022 Nov 23. Sci Transl Med. 2022. PMID: 36417486 Free PMC article.

9

Ablation of CaMKIIδ oxidation by CRISPR-Cas9 base editing as a therapy for cardiac disease.

Lebek S, Chemello F, Caravia XM, Tan W, Li H, Chen K, Xu L, Liu N, Bassel-Duby R, Olson EN. Lebek S, et al. Among authors: chen k. Science. 2023 Jan 13;379(6628):179-185. doi: 10.1126/science.ade1105. Epub 2023 Jan 12. Science. 2023. PMID: 36634166 Free PMC article.

10

Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice.

Chai AC, Cui M, Chemello F, Li H, Chen K, Tan W, Atmanli A, McAnally JR, Zhang Y, Xu L, Liu N, Bassel-Duby R, Olson EN. Chai AC, et al. Among authors: chen k. Nat Med. 2023 Feb;29(2):401-411. doi: 10.1038/s41591-022-02176-5. Epub 2023 Feb 16. Nat Med. 2023. PMID: 36797478 Free PMC article.

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