Bonhaus DW - Search Results

1

Reply to Matters Arising: In vivo effects of the alpha-synuclein misfolding inhibitor minzasolmin supports clinical development in Parkinson's disease.

Price DL, Khan A, Angers R, Cardenas A, Prato MK, Bani M, Bonhaus DW, Citron M, Biere AL. Price DL, et al. Among authors: bonhaus dw. NPJ Parkinsons Dis. 2024 Mar 14;10(1):60. doi: 10.1038/s41531-024-00658-6. NPJ Parkinsons Dis. 2024. PMID: 38486014 Free PMC article. No abstract available.

2

In vivo effects of the alpha-synuclein misfolding inhibitor minzasolmin supports clinical development in Parkinson's disease.

Price DL, Khan A, Angers R, Cardenas A, Prato MK, Bani M, Bonhaus DW, Citron M, Biere AL. Price DL, et al. Among authors: bonhaus dw. NPJ Parkinsons Dis. 2023 Jul 17;9(1):114. doi: 10.1038/s41531-023-00552-7. NPJ Parkinsons Dis. 2023. PMID: 37460603 Free PMC article.

3

NPT1220-312, a TLR2/TLR9 Small Molecule Antagonist, Inhibits Pro-Inflammatory Signaling, Cytokine Release, and NLRP3 Inflammasome Activation.

Habas A, Reddy Natala S, Bowden-Verhoek JK, Stocking EM, Price DL, Wrasidlo W, Bonhaus DW, Gill MB. Habas A, et al. Among authors: bonhaus dw. Int J Inflam. 2022 Feb 27;2022:2337363. doi: 10.1155/2022/2337363. eCollection 2022. Int J Inflam. 2022. PMID: 35265316 Free PMC article.

4

NPT520-34 improves neuropathology and motor deficits in a transgenic mouse model of Parkinson's disease.

Khan A, Johnson R, Wittmer C, Maile M, Tatsukawa K, Wong JL, Gill MB, Stocking EM, Natala SR, Paulino AD, Bowden-Verhoek JK, Wrasidlo W, Masliah E, Bonhaus DW, Price DL. Khan A, et al. Among authors: bonhaus dw. Brain. 2021 Dec 31;144(12):3692-3709. doi: 10.1093/brain/awab214. Brain. 2021. PMID: 34117864

5

Structure based design and synthesis of novel Toll-like Receptor 2 (TLR 2) lipid antagonists.

Natala SR, Habas A, Stocking EM, Orry A, Price DL, Gill MB, Bonhaus DW, Abagyan R, Wrasidlo W. Natala SR, et al. Among authors: bonhaus dw. Bioorg Med Chem Lett. 2021 May 15;40:127861. doi: 10.1016/j.bmcl.2021.127861. Epub 2021 Feb 23. Bioorg Med Chem Lett. 2021. PMID: 33636302

6

AC-186, a selective nonsteroidal estrogen receptor β agonist, shows gender specific neuroprotection in a Parkinson's disease rat model.

McFarland K, Price DL, Davis CN, Ma JN, Bonhaus DW, Burstein ES, Olsson R. McFarland K, et al. Among authors: bonhaus dw. ACS Chem Neurosci. 2013 Sep 18;4(9):1249-55. doi: 10.1021/cn400132u. Epub 2013 Aug 6. ACS Chem Neurosci. 2013. PMID: 23898966 Free PMC article.

7

Pimavanserin, a 5-HT2A receptor inverse agonist, reverses psychosis-like behaviors in a rodent model of Alzheimer's disease.

Price DL, Bonhaus DW, McFarland K. Price DL, et al. Among authors: bonhaus dw. Behav Pharmacol. 2012 Aug;23(4):426-33. doi: 10.1097/FBP.0b013e3283566082. Behav Pharmacol. 2012. PMID: 22750845

8

Discovery of potential antipsychotic agents possessing pro-cognitive properties.

Lameh J, McFarland K, Ohlsson J, Ek F, Piu F, Burstein ES, Tabatabaei A, Olsson R, Bradley SR, Bonhaus DW. Lameh J, et al. Among authors: bonhaus dw. Naunyn Schmiedebergs Arch Pharmacol. 2012 Mar;385(3):313-23. doi: 10.1007/s00210-011-0702-2. Epub 2011 Nov 15. Naunyn Schmiedebergs Arch Pharmacol. 2012. PMID: 22083558

9

Pimavanserin, a 5-HT2A inverse agonist, reverses psychosis-like behaviors in a rodent model of Parkinson's disease.

McFarland K, Price DL, Bonhaus DW. McFarland K, et al. Among authors: bonhaus dw. Behav Pharmacol. 2011 Oct;22(7):681-92. doi: 10.1097/FBP.0b013e32834aff98. Behav Pharmacol. 2011. PMID: 21921840

10

Differential regulation of muscarinic M1 receptors by orthosteric and allosteric ligands.

Davis CN, Bradley SR, Schiffer HH, Friberg M, Koch K, Tolf BR, Bonhaus DW, Lameh J. Davis CN, et al. Among authors: bonhaus dw. BMC Pharmacol. 2009 Dec 2;9:14. doi: 10.1186/1471-2210-9-14. BMC Pharmacol. 2009. PMID: 19951444 Free PMC article.

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