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Glutaminolysis is associated with mitochondrial pathway activation and can be therapeutically targeted in glioblastoma.
Miki K, Yagi M, Hatae R, Otsuji R, Miyazaki T, Goto K, Setoyama D, Fujioka Y, Sangatsuda Y, Kuga D, Higa N, Takajo T, Hajime Y, Akahane T, Tanimoto A, Hanaya R, Kunisaki Y, Uchiumi T, Yoshimoto K. Miki K, et al. Among authors: hatae r. Cancer Metab. 2024 Nov 19;12(1):35. doi: 10.1186/s40170-024-00364-0. Cancer Metab. 2024. PMID: 39563470 Free PMC article.
Hemizygous deletion of cyclin-dependent kinase inhibitor 2A/B with p16 immuno-negative and methylthioadenosine phosphorylase retention predicts poor prognosis in IDH-mutant adult glioma.
Otsuji R, Hata N, Yamamoto H, Kuga D, Hatae R, Sangatsuda Y, Fujioka Y, Noguchi N, Sako A, Togao O, Yoshitake T, Nakamizo A, Mizoguchi M, Yoshimoto K. Otsuji R, et al. Among authors: hatae r. Neurooncol Adv. 2024 May 8;6(1):vdae069. doi: 10.1093/noajnl/vdae069. eCollection 2024 Jan-Dec. Neurooncol Adv. 2024. PMID: 39022644 Free PMC article.
Soluble immune checkpoint factors reflect exhaustion of antitumor immunity and response to PD-1 blockade.
Hayashi H, Chamoto K, Hatae R, Kurosaki T, Togashi Y, Fukuoka K, Goto M, Chiba Y, Tomida S, Ota T, Haratani K, Takahama T, Tanizaki J, Yoshida T, Iwasa T, Tanaka K, Takeda M, Hirano T, Yoshida H, Ozasa H, Sakamori Y, Sakai K, Higuchi K, Uga H, Suminaka C, Hirai T, Nishio K, Nakagawa K, Honjo T. Hayashi H, et al. Among authors: hatae r. J Clin Invest. 2024 Apr 1;134(7):e168318. doi: 10.1172/JCI168318. J Clin Invest. 2024. PMID: 38557498 Free PMC article.
Liquid Biopsy for Glioma Using Cell-Free DNA in Cerebrospinal Fluid.
Otsuji R, Fujioka Y, Hata N, Kuga D, Hatae R, Sangatsuda Y, Nakamizo A, Mizoguchi M, Yoshimoto K. Otsuji R, et al. Among authors: hatae r. Cancers (Basel). 2024 Feb 29;16(5):1009. doi: 10.3390/cancers16051009. Cancers (Basel). 2024. PMID: 38473369 Free PMC article. Review.
Supramaximal Resection Can Prolong the Survival of Patients with Cortical Glioblastoma: A Volumetric Study.
Otsuji R, Hata N, Funakoshi Y, Kuga D, Togao O, Hatae R, Sangatsuda Y, Fujioka Y, Takigawa K, Sako A, Kikuchi K, Yoshitake T, Yamamoto H, Mizoguchi M, Yoshimoto K. Otsuji R, et al. Among authors: hatae r. Neurol Med Chir (Tokyo). 2023 Aug 15;63(8):364-374. doi: 10.2176/jns-nmc.2022-0351. Epub 2023 Jul 10. Neurol Med Chir (Tokyo). 2023. PMID: 37423755 Free PMC article.
Predicting TERT promoter mutation status using 1H-MR spectroscopy and stretched-exponential model of diffusion-weighted imaging in IDH-wildtype diffuse astrocytic glioma without intense enhancement.
Yamashita K, Hatae R, Kikuchi K, Kuga D, Hata N, Yamamoto H, Obara M, Yoshimoto K, Ishigami K, Togao O. Yamashita K, et al. Among authors: hatae r. Neuroradiology. 2023 Aug;65(8):1205-1213. doi: 10.1007/s00234-023-03177-y. Epub 2023 Jun 13. Neuroradiology. 2023. PMID: 37308686
Combination bezafibrate and nivolumab treatment of patients with advanced non-small cell lung cancer.
Tanaka K, Chamoto K, Saeki S, Hatae R, Ikematsu Y, Sakai K, Ando N, Sonomura K, Kojima S, Taketsuna M, Kim YH, Yoshida H, Ozasa H, Sakamori Y, Hirano T, Matsuda F, Hirai T, Nishio K, Sakagami T, Fukushima M, Nakanishi Y, Honjo T, Okamoto I. Tanaka K, et al. Among authors: hatae r. Sci Transl Med. 2022 Dec 14;14(675):eabq0021. doi: 10.1126/scitranslmed.abq0021. Epub 2022 Dec 14. Sci Transl Med. 2022. PMID: 36516270
61 results