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Page 1
Engineering of a Biologically Active Glycosylated Glucagon-Like Peptide-1 Analogue.
Chandrashekar C, Lin F, Nishiuchi Y, Mohammed SF, White BF, Arsenakis Y, Yuliantie E, Zhao P, van Dun S, Koijen A, Kajihara Y, Wootten D, Dodd GT, van den Bos LJ, Wade JD, Hossain MA. Chandrashekar C, et al. Among authors: wade jd. J Med Chem. 2024 May 9;67(9):7276-7282. doi: 10.1021/acs.jmedchem.4c00093. Epub 2024 Mar 11. J Med Chem. 2024. PMID: 38465973
Engineering of a Biologically Active Insulin Dimer.
Liu M, White BF, Praveen P, Li W, Lin F, Wu H, Li R, Delaine C, Forbes BE, Wade JD, Hossain MA. Liu M, et al. Among authors: wade jd. J Med Chem. 2021 Dec 9;64(23):17448-17454. doi: 10.1021/acs.jmedchem.1c01594. Epub 2021 Nov 19. J Med Chem. 2021. PMID: 34797669
Minimum active structure of insulin-like peptide 5.
Belgi A, Bathgate RA, Kocan M, Patil N, Zhang S, Tregear GW, Wade JD, Hossain MA. Belgi A, et al. Among authors: wade jd. J Med Chem. 2013 Dec 12;56(23):9509-16. doi: 10.1021/jm400924p. Epub 2013 Nov 21. J Med Chem. 2013. PMID: 24188028
Effects of C-Terminal B-Chain Modifications in a Relaxin 3 Agonist Analogue.
Praveen P, Tailhades J, Rosengren KJ, Liu M, Wade JD, Bathgate RAD, Hossain MA. Praveen P, et al. Among authors: wade jd. ACS Med Chem Lett. 2020 Oct 22;11(11):2336-2340. doi: 10.1021/acsmedchemlett.0c00456. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214850 Free PMC article.
Chemical Synthesis and Characterization of a Nonfibrillating Glycoglucagon.
Liu M, Zhao P, Uddin MH, Li W, Lin F, Chandrashekar C, Nishiuchi Y, Kajihara Y, Forbes BE, Wootten D, Wade JD, Hossain MA. Liu M, et al. Among authors: wade jd. Bioconjug Chem. 2021 Oct 20;32(10):2148-2153. doi: 10.1021/acs.bioconjchem.1c00419. Epub 2021 Sep 8. Bioconjug Chem. 2021. PMID: 34494823
Glycosylation Improves the Proteolytic Stability of Exenatide.
Chandrashekar C, Nishiuchi Y, White BF, Arsenakis Y, Lin F, McNeill SM, Zhao P, van Dun S, Koijen A, Kajihara Y, Wootten D, van den Bos LJ, Wade JD, Hossain MA. Chandrashekar C, et al. Among authors: wade jd. Bioconjug Chem. 2023 Jun 21;34(6):1014-1018. doi: 10.1021/acs.bioconjchem.3c00120. Epub 2023 May 16. Bioconjug Chem. 2023. PMID: 37192432
Engineering of a Novel Simplified Human Insulin-Like Peptide 5 Agonist.
Patil NA, Hughes RA, Rosengren KJ, Kocan M, Ang SY, Tailhades J, Separovic F, Summers RJ, Grosse J, Wade JD, Bathgate RA, Hossain MA. Patil NA, et al. Among authors: wade jd. J Med Chem. 2016 Mar 10;59(5):2118-25. doi: 10.1021/acs.jmedchem.5b01786. Epub 2016 Feb 12. J Med Chem. 2016. PMID: 26824523
286 results