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Engineering of a Biologically Active Glycosylated Glucagon-Like Peptide-1 Analogue.
Chandrashekar C, Lin F, Nishiuchi Y, Mohammed SF, White BF, Arsenakis Y, Yuliantie E, Zhao P, van Dun S, Koijen A, Kajihara Y, Wootten D, Dodd GT, van den Bos LJ, Wade JD, Hossain MA. Chandrashekar C, et al. Among authors: dodd gt. J Med Chem. 2024 May 9;67(9):7276-7282. doi: 10.1021/acs.jmedchem.4c00093. Epub 2024 Mar 11. J Med Chem. 2024. PMID: 38465973
Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.
Kyriakou E, Schmidt S, Dodd GT, Pfuhlmann K, Simonds SE, Lenhart D, Geerlof A, Schriever SC, De Angelis M, Schramm KW, Plettenburg O, Cowley MA, Tiganis T, Tschöp MH, Pfluger PT, Sattler M, Messias AC. Kyriakou E, et al. Among authors: dodd gt. J Med Chem. 2018 Dec 27;61(24):11144-11157. doi: 10.1021/acs.jmedchem.8b01224. Epub 2018 Dec 7. J Med Chem. 2018. PMID: 30525586
Pathogenic hypothalamic extracellular matrix promotes metabolic disease.
Beddows CA, Shi F, Horton AL, Dalal S, Zhang P, Ling CC, Yong VW, Loh K, Cho E, Karagiannis C, Rose AJ, Montgomery MK, Gregorevic P, Watt MJ, Packer NH, Parker BL, Brown RM, Moh ESX, Dodd GT. Beddows CA, et al. Among authors: dodd gt. Nature. 2024 Sep;633(8031):914-922. doi: 10.1038/s41586-024-07922-y. Epub 2024 Sep 18. Nature. 2024. PMID: 39294371 Free PMC article.
Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease.
Watt KI, Henstridge DC, Ziemann M, Sim CB, Montgomery MK, Samocha-Bonet D, Parker BL, Dodd GT, Bond ST, Salmi TM, Lee RS, Thomson RE, Hagg A, Davey JR, Qian H, Koopman R, El-Osta A, Greenfield JR, Watt MJ, Febbraio MA, Drew BG, Cox AG, Porrello ER, Harvey KF, Gregorevic P. Watt KI, et al. Among authors: dodd gt. Nat Commun. 2021 May 17;12(1):2887. doi: 10.1038/s41467-021-23240-7. Nat Commun. 2021. PMID: 34001905 Free PMC article.
32 results