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SMYD5 is a ribosomal methyltransferase that catalyzes RPL40 lysine methylation to enhance translation output and promote hepatocellular carcinoma.
Miao B, Ge L, He C, Wang X, Wu J, Li X, Chen K, Wan J, Xing S, Ren L, Shi Z, Liu S, Hu Y, Chen J, Yu Y, Feng L, Flores NM, Liang Z, Xu X, Wang R, Zhou J, Fan J, Xiang B, Li E, Mao Y, Cheng J, Zhao K, Mazur PK, Cai J, Lan F. Miao B, et al. Among authors: mazur pk. Cell Res. 2024 Sep;34(9):648-660. doi: 10.1038/s41422-024-01013-3. Epub 2024 Aug 5. Cell Res. 2024. PMID: 39103523 Free PMC article.
Atlas of Metastatic Gastric Cancer Links Ferroptosis to Disease Progression and Immunotherapy Response.
Cheng X, Dai E, Wu J, Flores NM, Chu Y, Wang R, Dang M, Xu Z, Han G, Liu Y, Chatterjee D, Hu C, Ying J, Du Y, Yang L, Guan X, Mo S, Cao X, Pei G, Jiang J, Lu X, Benitez AM, Waters RE, Pizzi MP, Shanbhag N, Fan Y, Peng F, Hanash SM, Calin G, Futreal A, Song S, Yee C, Mazur PK, Qin JJ, Ajani JA, Wang L. Cheng X, et al. Among authors: mazur pk. Gastroenterology. 2024 Aug 2:S0016-5085(24)05297-1. doi: 10.1053/j.gastro.2024.07.038. Online ahead of print. Gastroenterology. 2024. PMID: 39097198
SMYD5 methylation of rpL40 links ribosomal output to gastric cancer.
Park J, Wu J, Szkop KJ, Jeong J, Jovanovic P, Husmann D, Flores NM, Francis JW, Chen YC, Benitez AM, Zahn E, Song S, Ajani JA, Wang L, Singh K, Larsson O, Garcia BA, Topisirovic I, Gozani O, Mazur PK. Park J, et al. Among authors: mazur pk. Nature. 2024 Aug;632(8025):656-663. doi: 10.1038/s41586-024-07718-0. Epub 2024 Jul 24. Nature. 2024. PMID: 39048817
Author Correction: Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, Sánchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, Noël PB, Braren R, Erkan M, Kleeff J, Sipos B, Sayles LC, Heikenwalder M, Heßmann E, Ellenrieder V, Esposito I, Jacks T, Bradner JE, Khatri P, Sweet-Cordero EA, Attardi LD, Schmid RM, Schneider G, Sage J, Siveke JT. Mazur PK, et al. Nat Med. 2024 Jul;30(7):2090. doi: 10.1038/s41591-024-03054-y. Nat Med. 2024. PMID: 38816611 No abstract available.
Author Correction: Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis.
Casanova AG, Roth GS, Hausmann S, Lu X, Bischoff LJM, Froeliger EM, Belmudes L, Bourova-Flin E, Flores NM, Benitez AM, Chasan T, Caporicci M, Vayr J, Blanchet S, Ielasi F, Rousseaux S, Hainaut P, Gozani O, Le Romancer M, Couté Y, Palencia A, Mazur PK, Reynoird N. Casanova AG, et al. Among authors: mazur pk. Cell Discov. 2024 Mar 26;10(1):34. doi: 10.1038/s41421-024-00661-4. Cell Discov. 2024. PMID: 38531836 Free PMC article. No abstract available.
FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis.
Francis JW, Hausmann S, Ikram S, Yin K, Mealey-Farr R, Flores NM, Trinh AT, Chasan T, Thompson J, Mazur PK, Gozani O. Francis JW, et al. Among authors: mazur pk. Mol Cell. 2024 May 2;84(9):1753-1763.e7. doi: 10.1016/j.molcel.2024.02.037. Epub 2024 Mar 19. Mol Cell. 2024. PMID: 38508183
A Lung Cancer Mouse Model Database.
Cai L, Gao Y, DeBerardinis RJ, Acquaah-Mensah G, Aidinis V, Beane JE, Biswal S, Chen T, Concepcion-Crisol CP, Grüner BM, Jia D, Jones R, Kurie JM, Lee MG, Lindahl P, Lissanu Y, Lorz Lopez MC, Martinelli R, Mazur PK, Mazzilli SA, Mii S, Moll H, Moorehead R, Morrisey EE, Ng SR, Oser MG, Pandiri AR, Powell CA, Ramadori G, Santos Lafuente M, Snyder E, Sotillo R, Su KY, Taki T, Taparra K, Xia Y, van Veen E, Winslow MM, Xiao G, Rudin CM, Oliver TG, Xie Y, Minna JD. Cai L, et al. Among authors: mazur pk. bioRxiv [Preprint]. 2024 May 14:2024.02.28.582577. doi: 10.1101/2024.02.28.582577. bioRxiv. 2024. PMID: 38464291 Free PMC article. Preprint.
Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis.
Casanova AG, Roth GS, Hausmann S, Lu X, Bischoff LJM, Froeliger EM, Belmudes L, Bourova-Flin E, Flores NM, Benitez AM, Chasan T, Caporicci M, Vayr J, Blanchet S, Ielasi F, Rousseaux S, Hainaut P, Gozani O, Le Romancer M, Couté Y, Palencia A, Mazur PK, Reynoird N. Casanova AG, et al. Among authors: mazur pk. Cell Discov. 2024 Jan 31;10(1):12. doi: 10.1038/s41421-023-00644-x. Cell Discov. 2024. PMID: 38296970 Free PMC article.
Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis.
Casanova AG, Roth GS, Hausmann S, Lu X, Belmudes L, Bourova-Flin E, Flores NM, Benitez AM, Caporicci M, Vayr J, Blanchet S, Ielasi F, Rousseaux S, Hainaut P, Gozani O, Couté Y, Palencia A, Mazur PK, Reynoird N. Casanova AG, et al. Among authors: mazur pk. bioRxiv [Preprint]. 2023 Sep 18:2023.09.18.558201. doi: 10.1101/2023.09.18.558201. bioRxiv. 2023. Update in: Cell Discov. 2024 Jan 31;10(1):12. doi: 10.1038/s41421-023-00644-x. PMID: 37790557 Free PMC article. Updated. Preprint.
53 results