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An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.
Sheehan PW, Nadarajah CJ, Kanan MF, Patterson JN, Novotny B, Lawrence JH, King MW, Brase L, Inman CE, Yuede CM, Lee J, Patel TK, Harari O, Benitez BA, Davis AA, Musiek ES. Sheehan PW, et al. Among authors: yuede cm. Neuron. 2023 Aug 2;111(15):2383-2398.e7. doi: 10.1016/j.neuron.2023.05.006. Epub 2023 Jun 13. Neuron. 2023. PMID: 37315555 Free PMC article.
The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway.
Chen H, Ferguson CJ, Mitchell DC, Risch I, Titus A, Paulo JA, Hwang A, Beck LK, Lin TH, Gu W, Song SK, Yuede CM, Yano H, Griffith OL, Griffith M, Gygi SP, Bonni A, Kim AH. Chen H, et al. Among authors: yuede cm. Cell Rep. 2025 Jan 23;44(2):115231. doi: 10.1016/j.celrep.2025.115231. Online ahead of print. Cell Rep. 2025. PMID: 39862434 Free article.
Haploinsufficiency of lysosomal enzyme genes in Alzheimer's disease.
Benitez BA, Wallace CE, Patel M, Nykanen NP, Yuede CM, Eaton SL, Pottier C, Cetin A, Johnson M, Bevan MT, Gardiner WD, Edwards HM, Doherty BM, Harrigan RT, Kurian D, Wishart TM, Smith C, Cirrito JR, Sands MS. Benitez BA, et al. Among authors: yuede cm. bioRxiv [Preprint]. 2024 Nov 18:2024.11.16.623962. doi: 10.1101/2024.11.16.623962. bioRxiv. 2024. PMID: 39605615 Free PMC article. Preprint.
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Litvinchuk A, Suh JH, Guo JL, Lin K, Davis SS, Bien-Ly N, Tycksen E, Tabor GT, Serrano JR, Manis M, Bao X, Lee C, Bosch M, Perez EJ, Yuede CM, Cashikar AG, Ulrich JD, Di Paolo G, Holtzman DM. Litvinchuk A, et al. Among authors: yuede cm. Neuron. 2024 Jun 19;112(12):2079. doi: 10.1016/j.neuron.2024.05.021. Epub 2024 May 31. Neuron. 2024. PMID: 38823392 Free article. No abstract available.
52 results