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379 results

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A phase 1 trial of human telomerase reverse transcriptase (hTERT) vaccination combined with therapeutic strategies to control immune-suppressor mechanisms.
Zareian N, Eremin O, Pandha H, Baird R, Kwatra V, Funingana G, Verma C, Choy D, Hargreaves S, Moghimi P, Shepherd A, Lobo DN, Eremin J, Farzaneh F, Kordasti S, Spicer J. Zareian N, et al. Among authors: choy d. Exp Biol Med (Maywood). 2024 Jan 31;249:10021. doi: 10.3389/ebm.2024.10021. eCollection 2024. Exp Biol Med (Maywood). 2024. PMID: 38463391 Free PMC article. Clinical Trial.
Pre-treatment with systemic agents for advanced NSCLC elicits changes in the phenotype of autologous T cell therapy products.
O'Brien Gore C, Billman A, Hunjan S, Colebrook J, Choy D, Li W, Haynes J, Wade J, Hobern E, McDonald L, Papa S, Brugman M, Kordasti S, Montiel-Equihua C. O'Brien Gore C, et al. Among authors: choy d. Mol Ther Oncolytics. 2023 Nov 10;31:100749. doi: 10.1016/j.omto.2023.100749. eCollection 2023 Dec 19. Mol Ther Oncolytics. 2023. PMID: 38075248 Free PMC article.
Mutations in the splicing factor SF3B1 are linked to frequent emergence of HLA-DRlow/neg monocytes in lower-risk myelodysplastic neoplasms.
Winter S, Schneider M, Oelschlaegel U, Maggioni G, Riva E, Raddi MG, Bencini S, Peruzzi B, Choy D, Antunes Dos Reis R, Güse E, Lischer C, Vera J, Timms JA, Sompairac N, Sockel K, Poloni A, Tunger A, Della Porta MG, Santini V, Schmitz M, Platzbecker U, Kordasti S. Winter S, et al. Among authors: choy d. Leukemia. 2024 Jun;38(6):1427-1431. doi: 10.1038/s41375-024-02249-z. Epub 2024 Apr 17. Leukemia. 2024. PMID: 38632316 Free PMC article. No abstract available.
Genome-wide association study of anterior uveitis.
Koskimäki F, Ahokas O, Kajanne R, Saviauk KR, Elnahas A, Reigo A, Reis K, Esko T, Palta P, Leinonen S, Kettunen J, Liinamaa J, Karjalainen MK, Saarela V; Estonian Biobank Research Team Consortium; FinnGen Consortium; Estonian Biobank Research Team Consortium authors. Koskimäki F, et al. Br J Ophthalmol. 2024 Dec 27:bjo-2024-326037. doi: 10.1136/bjo-2024-326037. Online ahead of print. Br J Ophthalmol. 2024. PMID: 39732499
Novel loci and biomedical consequences of iron homoeostasis variation.
Allara E, Bell S, Smith R, Keene SJ, Gill D, Gaziano L, Morselli Gysi D, Wang F, Tragante V, Mason A, Karthikeyan S, Lumbers RT, Bonglack E, Ouwehand W, Roberts DJ, Dowsett J, Ostrowski SR, Larsen MH, Ullum H, Pedersen OB, Brunak S, Banasik K, Erikstrup C; DBDS Genomic Consortium; Mitchell J, Fuchsberger C, Pattaro C, Pramstaller PP, Girelli D, Arvas M, Toivonen J, Molnos S, Peters A, Polasek O, Rudan I, Hayward C, McDonnell C, Pirastu N, Wilson JF, van den Hurk K, Quee F, Ferrucci L, Bandinelli S, Tanaka T, Girotto G, Concas MP, Pecori A, Verweij N, van der Harst P, van de Vegte YJ, Kiemeney LA, Sweep FC, Galesloot TE, Sulem P, Gudbjartsson D, Ferkingstad E; FinnGen Consortium; Djousse L, Cho K, Inouye M, Burgess S, Benyamin B, Oexle K, Swinkels D, Stefansson K, Magnusson M, Ganna A, Gaziano M, Ivey K, Danesh J, Pereira A, Wood AM, Butterworth AS, Di Angelantonio E. Allara E, et al. Commun Biol. 2024 Dec 6;7(1):1631. doi: 10.1038/s42003-024-07115-3. Commun Biol. 2024. PMID: 39643614 Free PMC article.
Genetic susceptibility to acute viral bronchiolitis.
Pasanen A, Karjalainen MK, Korppi M, Hallman M, Rämet M; Research Project FinnGen. Pasanen A, et al. J Infect Dis. 2024 Sep 20:jiae467. doi: 10.1093/infdis/jiae467. Online ahead of print. J Infect Dis. 2024. PMID: 39299705
Airway tryptase levels inform the lack of clinical efficacy of the tryptase inhibitor MTPS9579A in asthma.
Rhee H, Henderson LM, Bauer RN, Wong K, Staton TL, Choy DF, Banerjee P, Poon V, Yoshida K, Chen C, Long K, Sperinde G, Laing ST, Jones NS, Glickstein SB, Dayal P, Fong A, Dash A, Pulka G, Leaker B, Singh D, Bradding P. Rhee H, et al. Among authors: choy df. Allergy. 2024 Nov;79(11):2993-3004. doi: 10.1111/all.16309. Epub 2024 Sep 9. Allergy. 2024. PMID: 39250147 Clinical Trial.
TWINGEN: protocol for an observational clinical biobank recall and biomarker cohort study to identify Finnish individuals with high risk of Alzheimer's disease.
Vuoksimaa E, Saari TT, Aaltonen A, Aaltonen S, Herukka SK, Iso-Markku P, Kokkola T, Kyttälä A, Kärkkäinen S, Liedes H, Ollikainen M, Palviainen T, Ruotsalainen I, Toivola A, Urjansson M, Vasankari T, Vähä-Ypyä H, Forsberg MM, Hiltunen M, Jalanko A, Kälviäinen R, Kuopio T, Lähteenmäki J, Nyberg P, Männikkö M, Serpi R, Siltanen S, Palotie A, Kaprio J, Runz H, Julkunen V; FinnGen. Vuoksimaa E, et al. BMJ Open. 2024 Jun 12;14(6):e081947. doi: 10.1136/bmjopen-2023-081947. BMJ Open. 2024. PMID: 38866570 Free PMC article.
379 results