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TRF2 as novel marker of tumor response to taxane-based therapy: from mechanistic insight to clinical implication.
Iachettini S, Terrenato I, Porru M, Di Vito S, Rizzo A, D'Angelo C, Petti E, Dinami R, Maresca C, Di Benedetto A, Palange A, Mulè A, Santoro A, Palazzo A, Fuso P, Stoppacciaro A, Vici P, Filomeno L, Di Lisa FS, Arcuri T, Krasniqi E, Fabi A, Biroccio A, Zizza P. Iachettini S, et al. Among authors: zizza p. J Exp Clin Cancer Res. 2024 Mar 9;43(1):75. doi: 10.1186/s13046-024-02998-w. J Exp Clin Cancer Res. 2024. PMID: 38459559 Free PMC article.
TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.
Biroccio A, Cherfils-Vicini J, Augereau A, Pinte S, Bauwens S, Ye J, Simonet T, Horard B, Jamet K, Cervera L, Mendez-Bermudez A, Poncet D, Grataroli R, de Rodenbeeke CT, Salvati E, Rizzo A, Zizza P, Ricoul M, Cognet C, Kuilman T, Duret H, Lépinasse F, Marvel J, Verhoeyen E, Cosset FL, Peeper D, Smyth MJ, Londoño-Vallejo A, Sabatier L, Picco V, Pages G, Scoazec JY, Stoppacciaro A, Leonetti C, Vivier E, Gilson E. Biroccio A, et al. Among authors: zizza p. Nat Cell Biol. 2013 Jul;15(7):818-28. doi: 10.1038/ncb2774. Epub 2013 Jun 23. Nat Cell Biol. 2013. PMID: 23792691
On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts.
Iachettini S, Stevens MF, Frigerio M, Hummersone MG, Hutchinson I, Garner TP, Searle MS, Wilson DW, Munde M, Nanjunda R, D'Angelo C, Zizza P, Rizzo A, Cingolani C, De Cicco F, Porru M, D'Incalci M, Leonetti C, Biroccio A, Salvati E. Iachettini S, et al. Among authors: zizza p. J Exp Clin Cancer Res. 2013 Sep 19;32(1):68. doi: 10.1186/1756-9966-32-68. J Exp Clin Cancer Res. 2013. PMID: 24330541 Free PMC article.
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.
Salvati E, Zizza P, Rizzo A, Iachettini S, Cingolani C, D'Angelo C, Porru M, Randazzo A, Pagano B, Novellino E, Pisanu ME, Stoppacciaro A, Spinella F, Bagnato A, Gilson E, Leonetti C, Biroccio A. Salvati E, et al. Among authors: zizza p. Nucleic Acids Res. 2014 Mar;42(5):2945-57. doi: 10.1093/nar/gkt1289. Epub 2013 Dec 11. Nucleic Acids Res. 2014. PMID: 24335081 Free PMC article.
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.
Salvati E, Rizzo A, Iachettini S, Zizza P, Cingolani C, D'Angelo C, Porru M, Mondello C, Aiello A, Farsetti A, Gilson E, Leonetti C, Biroccio A. Salvati E, et al. Among authors: zizza p. Nucleic Acids Res. 2015 Feb 18;43(3):1759-69. doi: 10.1093/nar/gkv006. Epub 2015 Jan 23. Nucleic Acids Res. 2015. PMID: 25618850 Free PMC article.
47 results