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18 results

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Page 1
Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development.
Kim T, Martínez-Bonet M, Wang Q, Hackert N, Sparks JA, Baglaenko Y, Koh B, Darbousset R, Laza-Briviesca R, Chen X, Aguiar VRC, Chiu DJ, Westra HJ, Gutierrez-Arcelus M, Weirauch MT, Raychaudhuri S, Rao DA, Nigrovic PA. Kim T, et al. Among authors: aguiar vrc. Nat Commun. 2024 Mar 9;15(1):2150. doi: 10.1038/s41467-024-46457-8. Nat Commun. 2024. PMID: 38459032 Free PMC article.
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.
Kang JB, Shen AZ, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta KA, Zhang F, Jonsson AH, Yazar S, Alquicira-Hernandez J, Khalili H, Ananthakrishnan AN, Jagadeesh K, Dey K; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Daly MJ, Xavier RJ, Donlin LT, Anolik JH, Powell JE, Rao DA, Brenner MB, Gutierrez-Arcelus M, Luo Y, Sakaue S, Raychaudhuri S. Kang JB, et al. Among authors: aguiar vrc. Nat Genet. 2023 Dec;55(12):2255-2268. doi: 10.1038/s41588-023-01586-6. Epub 2023 Nov 30. Nat Genet. 2023. PMID: 38036787 Free PMC article.
Rhinovirus infection of airway epithelial cells uncovers the non-ciliated subset as a likely driver of genetic risk to childhood-onset asthma.
Djeddi S, Fernandez-Salinas D, Huang GX, Aguiar VRC, Mohanty C, Kendziorski C, Gazal S, Boyce JA, Ober C, Gern JE, Barrett NA, Gutierrez-Arcelus M. Djeddi S, et al. Among authors: aguiar vrc. Cell Genom. 2024 Sep 11;4(9):100636. doi: 10.1016/j.xgen.2024.100636. Epub 2024 Aug 27. Cell Genom. 2024. PMID: 39197446 Free PMC article.
Rhinovirus infection of airway epithelial cells uncovers the non-ciliated subset as a likely driver of genetic susceptibility to childhood-onset asthma.
Djeddi S, Fernandez-Salinas D, Huang GX, Aguiar VRC, Mohanty C, Kendziorski C, Gazal S, Boyce J, Ober C, Gern J, Barrett N, Gutierrez-Arcelus M. Djeddi S, et al. Among authors: aguiar vrc. medRxiv [Preprint]. 2024 Feb 6:2024.02.02.24302068. doi: 10.1101/2024.02.02.24302068. medRxiv. 2024. Update in: Cell Genom. 2024 Sep 11;4(9):100636. doi: 10.1016/j.xgen.2024.100636 PMID: 38370648 Free PMC article. Updated. Preprint.
Functional genomics implicates natural killer cells in the pathogenesis of ankylosing spondylitis.
Chiñas M, Fernandez-Salinas D, Aguiar VRC, Nieto-Caballero VE, Lefton M, Nigrovic PA, Ermann J, Gutierrez-Arcelus M. Chiñas M, et al. Among authors: aguiar vrc. medRxiv [Preprint]. 2024 May 9:2023.09.21.23295912. doi: 10.1101/2023.09.21.23295912. medRxiv. 2024. Update in: HGG Adv. 2025 Jan 9;6(1):100375. doi: 10.1016/j.xhgg.2024.100375 PMID: 37808698 Free PMC article. Updated. Preprint.
High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus.
Nigrovic PA, Wang Q, Kim T, Martinez-Bonet M, Aguiar VRC, Sim S, Cui J, Sparks JA, Chen X, Todd M, Wauford B, Marion MC, Langefeld CD, Weirauch MT, Gutierrez-Arcelus M. Nigrovic PA, et al. Among authors: aguiar vrc. bioRxiv [Preprint]. 2024 Apr 12:2023.08.16.553538. doi: 10.1101/2023.08.16.553538. bioRxiv. 2024. Update in: Nat Commun. 2024 Aug 9;15(1):6804. doi: 10.1038/s41467-024-50710-5 PMID: 37645953 Free PMC article. Updated. Preprint.
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.
Kang JB, Shen AZ, Sakaue S, Luo Y, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta K, Zhang F, Jonsson AH, Yazar S, Alquicira-Hernandez J, Khalili H, Ananthakrishnan AN, Jagadeesh K, Dey K; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Daly MJ, Xavier RJ, Donlin LT, Anolik JH, Powell JE, Rao DA, Brenner MB, Gutierrez-Arcelus M, Raychaudhuri S. Kang JB, et al. Among authors: aguiar vrc. medRxiv [Preprint]. 2023 Mar 20:2023.03.14.23287257. doi: 10.1101/2023.03.14.23287257. medRxiv. 2023. Update in: Nat Genet. 2023 Dec;55(12):2255-2268. doi: 10.1038/s41588-023-01586-6 PMID: 36993194 Free PMC article. Updated. Preprint.
18 results