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Biophysical library screening using a Thermo-FMN assay to identify and characterize Clostridioides difficile FabK inhibitors.
Biochem Biophys Res Commun. 2024 Apr 23;705:149740. doi: 10.1016/j.bbrc.2024.149740. Epub 2024 Feb 29.
Biochem Biophys Res Commun. 2024.
PMID: 38458032
In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy.
Dureja C, Rutherford JT, Pavel FB, Norseeda K, Prah I, Sun D, Hevener KE, Hurdle JG.
Dureja C, et al.
Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0122223. doi: 10.1128/aac.01222-23. Epub 2024 Jan 24.
Antimicrob Agents Chemother. 2024.
PMID: 38265216
Free PMC article.
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In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) Inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy.
Dureja C, Rutherford JT, Pavel FBA, Norseeda K, Prah I, Sun D, Hevener KE, Hurdle JG.
Dureja C, et al. Among authors: pavel fba.
bioRxiv [Preprint]. 2023 Sep 22:2023.09.22.559005. doi: 10.1101/2023.09.22.559005.
bioRxiv. 2023.
Update in:
Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0122223. doi: 10.1128/aac.01222-23
PMID: 37790427
Free PMC article.
Updated.
Preprint.
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