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A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer.
Jung P, Glaser SP, Han J, Popa A, Pisarsky L, Feng N, Geyer A, Haderk F, Alpar D, Bristow C, Schmittner S, Traexler PE, Mahendra M, Poehn B, Gandhi P, Fiorelli R, Awate S, Budano N, Martin F, Albrecht C, Drobits-Handl B, Anand SS, Kasturirangan S, Trapani F, Schweifer N, Marszalek JR, Tontsch-Grunt U, Pearson M, Heffernan TP, Kraut N, Vellano CP, García-Martínez JM. Jung P, et al. Among authors: kasturirangan s. MAbs. 2024 Jan-Dec;16(1):2438173. doi: 10.1080/19420862.2024.2438173. Epub 2024 Dec 9. MAbs. 2024. PMID: 39654063 Free PMC article.
GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function.
Ray P, Jaiswal S, Ferrer-Torres D, Wang Z, Nancarrow D, Curtin M, Martinho MS, Lacy SM, Kasturirangan S, Thomas D, Spence JR, Truttmann MC, Lagisetty KH, Lawrence TS, Wang TD, Beer DG, Ray D. Ray P, et al. Among authors: kasturirangan s. Mol Cancer Res. 2024 Nov 1;22(11):996-1010. doi: 10.1158/1541-7786.MCR-24-0361. Mol Cancer Res. 2024. PMID: 39018356
ISG15/GRAIL1/CD3 axis influences survival of patients with esophageal adenocarcinoma.
McEwen DP, Ray P, Nancarrow DJ, Wang Z, Kasturirangan S, Abdullah S, Balan A, Hoskeri R, Thomas D, Lawrence TS, Beer DG, Lagisetty KH, Ray D. McEwen DP, et al. Among authors: kasturirangan s. JCI Insight. 2024 May 23;9(13):e179315. doi: 10.1172/jci.insight.179315. JCI Insight. 2024. PMID: 38781019 Free PMC article.
An adapted consensus protein design strategy for identifying globally optimal biotherapeutics.
Liu Y, Tsang K, Mays M, Hansen G, Chiecko J, Crames M, Wei Y, Zhou W, Fredrick C, Hu J, Liu D, Gebhard D, Huang ZF, Datar A, Kronkaitis A, Gueneva-Boucheva K, Seeliger D, Han F, Sen S, Kasturirangan S, Scheer JM, Nixon AE, Panavas T, Marlow MS, Kumar S. Liu Y, et al. Among authors: kasturirangan s. MAbs. 2022 Jan-Dec;14(1):2073632. doi: 10.1080/19420862.2022.2073632. MAbs. 2022. PMID: 35613320 Free PMC article.
24 results