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Page 1
Autophagy Contributes to Homeostasis in Esophageal Epithelium Where High Autophagic Vesicle Level Marks Basal Cells With Limited Proliferation and Enhanced Self-Renewal Potential.
Klochkova A, Karami AL, Fuller AD, Parham LR, Panchani SR, Natarajan S, Jackson JL, Mu A, Tan Y, Cai KQ, Klein-Szanto AJ, Muir AB, Tétreault MP, Graña X, Hamilton KE, Whelan KA. Klochkova A, et al. Among authors: whelan ka. Cell Mol Gastroenterol Hepatol. 2024;18(1):15-40. doi: 10.1016/j.jcmgh.2024.02.018. Epub 2024 Mar 5. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38452871 Free PMC article.
Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities.
Kagawa S, Natsuizaka M, Whelan KA, Facompre N, Naganuma S, Ohashi S, Kinugasa H, Egloff AM, Basu D, Gimotty PA, Klein-Szanto AJ, Bass AJ, Wong KK, Diehl JA, Rustgi AK, Nakagawa H. Kagawa S, et al. Among authors: whelan ka. Oncogene. 2015 Apr 30;34(18):2347-59. doi: 10.1038/onc.2014.169. Epub 2014 Jun 16. Oncogene. 2015. PMID: 24931169 Free PMC article.
ATG7 Gene Expression as a Novel Tissue Biomarker in Eosinophilic Esophagitis.
Merves JF, Whelan KA, Benitez AJ, Muir AB, Furuta GT, Wang ML, Falk GW, Spergel JM, Nakagawa H. Merves JF, et al. Among authors: whelan ka. Am J Gastroenterol. 2016 Jan;111(1):151-3. doi: 10.1038/ajg.2015.404. Am J Gastroenterol. 2016. PMID: 26785669 Free PMC article. No abstract available.
Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis.
Whelan KA, Merves JF, Giroux V, Tanaka K, Guo A, Chandramouleeswaran PM, Benitez AJ, Dods K, Que J, Masterson JC, Fernando SD, Godwin BC, Klein-Szanto AJ, Chikwava K, Ruchelli ED, Hamilton KE, Muir AB, Wang ML, Furuta GT, Falk GW, Spergel JM, Nakagawa H. Whelan KA, et al. Gut. 2017 Jul;66(7):1197-1207. doi: 10.1136/gutjnl-2015-310341. Epub 2016 Feb 16. Gut. 2017. PMID: 26884425 Free PMC article.
ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds.
Tanaka K, Whelan KA, Chandramouleeswaran PM, Kagawa S, Rustgi SL, Noguchi C, Guha M, Srinivasan S, Amanuma Y, Ohashi S, Muto M, Klein-Szanto AJ, Noguchi E, Avadhani NG, Nakagawa H. Tanaka K, et al. Among authors: whelan ka. Am J Cancer Res. 2016 Mar 15;6(4):781-96. eCollection 2016. Am J Cancer Res. 2016. PMID: 27186430 Free PMC article.
Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance.
Whelan KA, Chandramouleeswaran PM, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, Darling DS, Kita Y, Natsugoe S, Winkler JD, Klein-Szanto AJ, Amaravadi RK, Avadhani NG, Rustgi AK, Nakagawa H. Whelan KA, et al. Oncogene. 2017 Aug 24;36(34):4843-4858. doi: 10.1038/onc.2017.102. Epub 2017 Apr 17. Oncogene. 2017. PMID: 28414310 Free PMC article.
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