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Synthetic reversed sequences reveal default genomic states.
Camellato BR, Brosh R, Ashe HJ, Maurano MT, Boeke JD. Camellato BR, et al. Among authors: boeke jd. Nature. 2024 Apr;628(8007):373-380. doi: 10.1038/s41586-024-07128-2. Epub 2024 Mar 6. Nature. 2024. PMID: 38448583 Free PMC article.
GENOME ENGINEERING. The Genome Project-Write.
Boeke JD, Church G, Hessel A, Kelley NJ, Arkin A, Cai Y, Carlson R, Chakravarti A, Cornish VW, Holt L, Isaacs FJ, Kuiken T, Lajoie M, Lessor T, Lunshof J, Maurano MT, Mitchell LA, Rine J, Rosser S, Sanjana NE, Silver PA, Valle D, Wang H, Way JC, Yang L. Boeke JD, et al. Science. 2016 Jul 8;353(6295):126-7. doi: 10.1126/science.aaf6850. Epub 2016 Jun 2. Science. 2016. PMID: 27256881 No abstract available.
Heterozygous diploid and interspecies SCRaMbLEing.
Shen MJ, Wu Y, Yang K, Li Y, Xu H, Zhang H, Li BZ, Li X, Xiao WH, Zhou X, Mitchell LA, Bader JS, Yuan Y, Boeke JD. Shen MJ, et al. Among authors: boeke jd. Nat Commun. 2018 May 22;9(1):1934. doi: 10.1038/s41467-018-04157-0. Nat Commun. 2018. PMID: 29789590 Free PMC article.
In vitro DNA SCRaMbLE.
Wu Y, Zhu RY, Mitchell LA, Ma L, Liu R, Zhao M, Jia B, Xu H, Li YX, Yang ZM, Ma Y, Li X, Liu H, Liu D, Xiao WH, Zhou X, Li BZ, Yuan YJ, Boeke JD. Wu Y, et al. Among authors: boeke jd. Nat Commun. 2018 May 22;9(1):1935. doi: 10.1038/s41467-018-03743-6. Nat Commun. 2018. PMID: 29789594 Free PMC article.
A versatile platform for locus-scale genome rewriting and verification.
Brosh R, Laurent JM, Ordoñez R, Huang E, Hogan MS, Hitchcock AM, Mitchell LA, Pinglay S, Cadley JA, Luther RD, Truong DM, Boeke JD, Maurano MT. Brosh R, et al. Among authors: boeke jd. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2023952118. doi: 10.1073/pnas.2023952118. Proc Natl Acad Sci U S A. 2021. PMID: 33649239 Free PMC article.
De novo assembly and delivery to mouse cells of a 101 kb functional human gene.
Mitchell LA, McCulloch LH, Pinglay S, Berger H, Bosco N, Brosh R, Bulajić M, Huang E, Hogan MS, Martin JA, Mazzoni EO, Davoli T, Maurano MT, Boeke JD. Mitchell LA, et al. Among authors: boeke jd. Genetics. 2021 May 17;218(1):iyab038. doi: 10.1093/genetics/iyab038. Genetics. 2021. PMID: 33742653 Free PMC article.
The role of retrotransposable elements in ageing and age-associated diseases.
Gorbunova V, Seluanov A, Mita P, McKerrow W, Fenyö D, Boeke JD, Linker SB, Gage FH, Kreiling JA, Petrashen AP, Woodham TA, Taylor JR, Helfand SL, Sedivy JM. Gorbunova V, et al. Among authors: boeke jd. Nature. 2021 Aug;596(7870):43-53. doi: 10.1038/s41586-021-03542-y. Epub 2021 Aug 4. Nature. 2021. PMID: 34349292 Free PMC article. Review.
422 results