Woon ECY - Search Results

1

Synergistic combination of antimicrobial peptide and isoniazid as inhalable dry powder formulation against multi-drug resistant tuberculosis.

Shao Z, Tam KK, Achalla VPK, Woon ECY, Mason AJ, Chow SF, Yam WC, Lam JKW. Shao Z, et al. Among authors: woon ecy. Int J Pharm. 2024 Apr 10;654:123960. doi: 10.1016/j.ijpharm.2024.123960. Epub 2024 Mar 4. Int J Pharm. 2024. PMID: 38447778 Free article.

2

Inhibition of AlkB Nucleic Acid Demethylases: Promising New Epigenetic Targets.

Perry GS, Das M, Woon ECY. Perry GS, et al. Among authors: woon ecy. J Med Chem. 2021 Dec 9;64(23):16974-17003. doi: 10.1021/acs.jmedchem.1c01694. Epub 2021 Nov 18. J Med Chem. 2021. PMID: 34792334 Review.

3

Micro cell vesicle technology (mCVT): a novel hybrid system of gene delivery for hard-to-transfect (HTT) cells.

Ou YH , Zou S , Goh WJ , Chong SY , Venkatesan G , Wacker MG , Storm G , Wang JW , Czarny B , Pastorin G , Woon ECY . Ou YH , et al. Among authors: woon ecy. Nanoscale. 2020 Sep 21;12(35):18022-18030. doi: 10.1039/d0nr03784b. Epub 2020 Aug 28. Nanoscale. 2020. PMID: 32857097

4

A general strategy exploiting m5C duplex-remodelling effect for selective detection of RNA and DNA m5C methyltransferase activity in cells.

Yang T, Low JJA, Woon ECY. Yang T, et al. Among authors: woon ecy. Nucleic Acids Res. 2020 Jan 10;48(1):e5. doi: 10.1093/nar/gkz1047. Nucleic Acids Res. 2020. PMID: 31691820 Free PMC article.

5

A fluorescent methylation-switchable probe for highly sensitive analysis of FTO N ⁶-methyladenosine demethylase activity in cells.

Cheong A, Low JJA, Lim A, Yen PM, Woon ECY. Cheong A, et al. Among authors: woon ecy. Chem Sci. 2018 Aug 7;9(36):7174-7185. doi: 10.1039/c8sc02163e. eCollection 2018 Sep 28. Chem Sci. 2018. PMID: 30288236 Free PMC article.

6

Multiprotein Dynamic Combinatorial Chemistry: A Strategy for the Simultaneous Discovery of Subfamily-Selective Inhibitors for Nucleic Acid Demethylases FTO and ALKBH3.

Das M, Yang T, Dong J, Prasetya F, Xie Y, Wong KHQ, Cheong A, Woon ECY. Das M, et al. Among authors: woon ecy. Chem Asian J. 2018 Oct 4;13(19):2854-2867. doi: 10.1002/asia.201800729. Epub 2018 Sep 14. Chem Asian J. 2018. PMID: 29917331

7

Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity.

Lim A, Zhou J, Sinha RA, Singh BK, Ghosh S, Lim KH, Chow PK, Woon ECY, Yen PM. Lim A, et al. Among authors: woon ecy. Biochem Biophys Res Commun. 2016 Oct 21;479(3):476-481. doi: 10.1016/j.bbrc.2016.09.086. Epub 2016 Sep 17. Biochem Biophys Res Commun. 2016. PMID: 27651333

8

N(6)-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5.

Zou S, Toh JD, Wong KH, Gao YG, Hong W, Woon EC. Zou S, et al. Sci Rep. 2016 May 9;6:25677. doi: 10.1038/srep25677. Sci Rep. 2016. PMID: 27156733 Free PMC article.

9

A methylation-switchable conformational probe for the sensitive and selective detection of RNA demethylase activity.

Yang T, Cheong A, Mai X, Zou S, Woon EC. Yang T, et al. Chem Commun (Camb). 2016 May 4;52(36):6181-4. doi: 10.1039/c6cc01045h. Epub 2016 Apr 14. Chem Commun (Camb). 2016. PMID: 27074833

10

Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro.

Paine HA, Nathubhai A, Woon EC, Sunderland PT, Wood PJ, Mahon MF, Lloyd MD, Thompson AS, Haikarainen T, Narwal M, Lehtiö L, Threadgill MD. Paine HA, et al. Bioorg Med Chem. 2015 Sep 1;23(17):5891-908. doi: 10.1016/j.bmc.2015.06.061. Epub 2015 Jul 2. Bioorg Med Chem. 2015. PMID: 26189030

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