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Shotgun metagenomics and systemic targeted metabolomics highlight indole-3-propionic acid as a protective gut microbial metabolite against influenza infection.
Heumel S, de Rezende Rodovalho V, Urien C, Specque F, Brito Rodrigues P, Robil C, Delval L, Sencio V, Descat A, Deruyter L, Ferreira S, Gomes Machado M, Barthelemy A, Angulo FS, Haas JT, Goosens JF, Wolowczuk I, Grangette C, Rouillé Y, Grimaud G, Lenski M, Hennart B, Ramirez Vinolo MA, Trottein F. Heumel S, et al. Among authors: deruyter l. Gut Microbes. 2024 Jan-Dec;16(1):2325067. doi: 10.1080/19490976.2024.2325067. Epub 2024 Mar 6. Gut Microbes. 2024. PMID: 38445660 Free PMC article.
Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection.
Beshara R, Sencio V, Soulard D, Barthélémy A, Fontaine J, Pinteau T, Deruyter L, Ismail MB, Paget C, Sirard JC, Trottein F, Faveeuw C. Beshara R, et al. Among authors: deruyter l. PLoS Pathog. 2018 Oct 29;14(10):e1007360. doi: 10.1371/journal.ppat.1007360. eCollection 2018 Oct. PLoS Pathog. 2018. PMID: 30372491 Free PMC article.
Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues.
Ayari A, Rosa-Calatrava M, Lancel S, Barthelemy J, Pizzorno A, Mayeuf-Louchart A, Baron M, Hot D, Deruyter L, Soulard D, Julien T, Faveeuw C, Molendi-Coste O, Dombrowicz D, Sedano L, Sencio V, Le Goffic R, Trottein F, Wolowczuk I. Ayari A, et al. Among authors: deruyter l. Commun Biol. 2020 May 14;3(1):237. doi: 10.1038/s42003-020-0965-6. Commun Biol. 2020. PMID: 32409640 Free PMC article.
Influenza Virus Infection Impairs the Gut's Barrier Properties and Favors Secondary Enteric Bacterial Infection through Reduced Production of Short-Chain Fatty Acids.
Sencio V, Gallerand A, Gomes Machado M, Deruyter L, Heumel S, Soulard D, Barthelemy J, Cuinat C, Vieira AT, Barthelemy A, Tavares LP, Guinamard R, Ivanov S, Grangette C, Teixeira MM, Foligné B, Wolowczuk I, Le Goffic R, Thomas M, Trottein F. Sencio V, et al. Among authors: deruyter l. Infect Immun. 2021 Aug 16;89(9):e0073420. doi: 10.1128/IAI.00734-20. Epub 2021 Aug 16. Infect Immun. 2021. PMID: 33820816 Free PMC article.
Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice.
Belouzard S, Machelart A, Sencio V, Vausselin T, Hoffmann E, Deboosere N, Rouillé Y, Desmarets L, Séron K, Danneels A, Robil C, Belloy L, Moreau C, Piveteau C, Biela A, Vandeputte A, Heumel S, Deruyter L, Dumont J, Leroux F, Engelmann I, Alidjinou EK, Hober D, Brodin P, Beghyn T, Trottein F, Deprez B, Dubuisson J. Belouzard S, et al. Among authors: deruyter l. PLoS Pathog. 2022 May 19;18(5):e1010498. doi: 10.1371/journal.ppat.1010498. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35587469 Free PMC article.
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