Ashwell JD - Search Results

1

Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4⁺ T cells.

Park JE, Kim TS, Zeng Y, Mikolaj M, Il Ahn J, Alam MS, Monnie CM, Shi V, Zhou M, Chun TW, Maldarelli F, Narayan K, Ahn J, Ashwell JD, Strebel K, Lee KS. Park JE, et al. Among authors: ashwell jd. Nat Commun. 2024 Mar 5;15(1):2017. doi: 10.1038/s41467-024-46306-8. Nat Commun. 2024. PMID: 38443376 Free PMC article.

2

Identification and characterization of polyclonal αβ-T cells with dendritic cell properties.

Kuka M, Munitic I, Ashwell JD. Kuka M, et al. Among authors: ashwell jd. Nat Commun. 2012;3:1223. doi: 10.1038/ncomms2223. Nat Commun. 2012. PMID: 23187623 Free PMC article.

3

Counter-regulation of T cell effector function by differentially activated p38.

Alam MS, Gaida MM, Ogawa Y, Kolios AG, Lasitschka F, Ashwell JD. Alam MS, et al. Among authors: ashwell jd. J Exp Med. 2014 Jun 2;211(6):1257-70. doi: 10.1084/jem.20131917. Epub 2014 May 26. J Exp Med. 2014. PMID: 24863062 Free PMC article.

4

Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.

Alam MS, Gaida MM, Bergmann F, Lasitschka F, Giese T, Giese NA, Hackert T, Hinz U, Hussain SP, Kozlov SV, Ashwell JD. Alam MS, et al. Among authors: ashwell jd. Nat Med. 2015 Nov;21(11):1337-43. doi: 10.1038/nm.3957. Epub 2015 Oct 19. Nat Med. 2015. PMID: 26479921 Free PMC article.

5

Discovery and Characterization of a Biologically Active Non-ATP-Competitive p38 MAP Kinase Inhibitor.

Wilson BA, Alam MS, Guszczynski T, Jakob M, Shenoy SR, Mitchell CA, Goncharova EI, Evans JR, Wipf P, Liu G, Ashwell JD, O'Keefe BR. Wilson BA, et al. Among authors: ashwell jd. J Biomol Screen. 2016 Mar;21(3):277-89. doi: 10.1177/1087057115615518. Epub 2015 Nov 4. J Biomol Screen. 2016. PMID: 26538432 Free PMC article.

6

Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation.

Alam MS, Gaida MM, Debnath S, Tagad HD, Miller Jenkins LM, Appella E, Rahman MJ, Ashwell JD. Alam MS, et al. Among authors: ashwell jd. PLoS Biol. 2018 Jan 22;16(1):e2004111. doi: 10.1371/journal.pbio.2004111. eCollection 2018 Jan. PLoS Biol. 2018. PMID: 29357353 Free PMC article.

7

TNF plays a crucial role in inflammation by signaling via T cell TNFR2.

Alam MS, Otsuka S, Wong N, Abbasi A, Gaida MM, Fan Y, Meerzaman D, Ashwell JD. Alam MS, et al. Among authors: ashwell jd. Proc Natl Acad Sci U S A. 2021 Dec 14;118(50):e2109972118. doi: 10.1073/pnas.2109972118. Proc Natl Acad Sci U S A. 2021. PMID: 34873037 Free PMC article.

8

Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4⁺ T cells.

Park JE, Kim TS, Zeng Y, Monnie CM, Alam MS, Zhou M, Mikolaj M, Maldarelli F, Narayan K, Ahn J, Ashwell JD, Strebel K, Lee KS. Park JE, et al. Among authors: ashwell jd. Res Sq [Preprint]. 2023 Aug 22:rs.3.rs-2924123. doi: 10.21203/rs.3.rs-2924123/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Mar 5;15(1):2017. doi: 10.1038/s41467-024-46306-8 PMID: 37645926 Free PMC article. Updated. Preprint.

9

Genomic instability in Gadd45a-deficient mice.

Hollander MC, Sheikh MS, Bulavin DV, Lundgren K, Augeri-Henmueller L, Shehee R, Molinaro TA, Kim KE, Tolosa E, Ashwell JD, Rosenberg MP, Zhan Q, Fernández-Salguero PM, Morgan WF, Deng CX, Fornace AJ Jr. Hollander MC, et al. Among authors: ashwell jd. Nat Genet. 1999 Oct;23(2):176-84. doi: 10.1038/13802. Nat Genet. 1999. PMID: 10508513

10

Exploiting the apoptotic process for management of HIV: are we there yet?

Yang Y, Ashwell JD. Yang Y, et al. Among authors: ashwell jd. Apoptosis. 2001 Feb-Apr;6(1-2):139-46. doi: 10.1023/a:1009600901706. Apoptosis. 2001. PMID: 11321037 Review.

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