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Mtb HLA-E-tetramer-sorted CD8+ T cells have a diverse TCR repertoire.
Voogd L, Drittij AMHF, Dingenouts CKE, Franken KLMC, Unen VV, van Meijgaarden KE, Ruibal P, Hagedoorn RS, Leitner JA, Steinberger P, Heemskerk MHM, Davis MM, Scriba TJ, Ottenhoff THM, Joosten SA. Voogd L, et al. Among authors: hagedoorn rs. iScience. 2024 Feb 15;27(3):109233. doi: 10.1016/j.isci.2024.109233. eCollection 2024 Mar 15. iScience. 2024. PMID: 38439958 Free PMC article.
An HLA-A*11:01-Binding Neoantigen from Mutated NPM1 as Target for TCR Gene Therapy in AML.
van der Lee DI, Koutsoumpli G, Reijmers RM, Honders MW, de Jong RCM, Remst DFG, Wachsmann TLA, Hagedoorn RS, Franken KLMC, Kester MGD, Harber KJ, Roelofsen LM, Schouten AM, Mulder A, Drijfhout JW, Veelken H, van Veelen PA, Heemskerk MHM, Falkenburg JHF, Griffioen M. van der Lee DI, et al. Among authors: hagedoorn rs. Cancers (Basel). 2021 Oct 27;13(21):5390. doi: 10.3390/cancers13215390. Cancers (Basel). 2021. PMID: 34771556 Free PMC article.
Identification of a coordinated CD8 and CD4 T cell response directed against mismatched HLA Class I causing severe acute graft-versus-host disease.
Amir AL, Hagedoorn RS, van Luxemburg-Heijs SA, Marijt EW, Kruisselbrink AB, Frederik Falkenburg JH, Heemskerk MH. Amir AL, et al. Among authors: hagedoorn rs. Biol Blood Marrow Transplant. 2012 Feb;18(2):210-9. doi: 10.1016/j.bbmt.2011.10.018. Epub 2011 Oct 19. Biol Blood Marrow Transplant. 2012. PMID: 22015995 Free article. Clinical Trial.
Comparing CAR and TCR engineered T cell performance as a function of tumor cell exposure.
Wachsmann TLA, Wouters AK, Remst DFG, Hagedoorn RS, Meeuwsen MH, van Diest E, Leusen J, Kuball J, Falkenburg JHF, Heemskerk MHM. Wachsmann TLA, et al. Among authors: hagedoorn rs. Oncoimmunology. 2022 Feb 1;11(1):2033528. doi: 10.1080/2162402X.2022.2033528. eCollection 2022. Oncoimmunology. 2022. PMID: 35127255 Free PMC article.
47 results