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A computational approach to rapidly design peptides that detect SARS-CoV-2 surface protein S.
Hajikarimlou M, Hooshyar M, Moutaoufik MT, Aly KA, Azad T, Takallou S, Jagadeesan S, Phanse S, Said KB, Samanfar B, Bell JC, Dehne F, Babu M, Golshani A. Hajikarimlou M, et al. Among authors: azad t. NAR Genom Bioinform. 2022 Aug 22;4(3):lqac058. doi: 10.1093/nargab/lqac058. eCollection 2022 Sep. NAR Genom Bioinform. 2022. PMID: 36004308 Free PMC article.
A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion.
Nouri K, Azad T, Lightbody E, Khanal P, Nicol CJ, Yang X. Nouri K, et al. Among authors: azad t. FASEB J. 2019 Nov;33(11):12487-12499. doi: 10.1096/fj.201901343R. Epub 2019 Aug 20. FASEB J. 2019. PMID: 31431076 Free PMC article.
In summary, we have developed a new LATS BS for cancer biology and therapeutics research and uncovered a novel ALK-LATS-YAP/TAZ signaling axis that may play important roles in cancer and possibly other biologic processes.-Nouri, K., Azad, T., Lightbody, E., Khanal, …
In summary, we have developed a new LATS BS for cancer biology and therapeutics research and uncovered a novel ALK-LATS-YAP/TAZ signaling ax …
Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies.
Azad T, Rezaei R, Singaravelu R, Pelin A, Boulton S, Petryk J, Onsu KA, Martin NT, Hoskin V, Ghahremani M, Marotel M, Marius R, He X, Crupi MJF, Hoang HD, Nik-Akhtar A, Ahmadi M, Zamani NK, Golshani A, Alain T, Greer P, Ardolino M, Dickinson BC, Tai LH, Ilkow CS, Bell JC. Azad T, et al. Nat Commun. 2023 May 26;14(1):3035. doi: 10.1038/s41467-023-38651-x. Nat Commun. 2023. PMID: 37236967 Free PMC article.
Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy via lipid modulation of the tumor microenvironment.
Surendran A, Jamalkhah M, Poutou J, Birtch R, Lawson C, Dave J, Crupi MJF, Mayer J, Taylor V, Petryk J, de Souza CT, Moodie N, Billingsley JL, Austin B, Cormack N, Blamey N, Rezaei R, McCloskey CW, Fekete EEF, Birdi HK, Neault S, Jamieson TR, Wylie B, Tucker S, Azad T, Vanderhyden B, Tai LH, Bell JC, Ilkow CS. Surendran A, et al. Among authors: azad t. Front Immunol. 2023 Mar 10;14:1099459. doi: 10.3389/fimmu.2023.1099459. eCollection 2023. Front Immunol. 2023. PMID: 36969187 Free PMC article.
A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection.
Boulton S, Poutou J, Gill R, Alluqmani N, He X, Singaravelu R, Crupi MJF, Petryk J, Austin B, Angka L, Taha Z, Teo I, Singh S, Jamil R, Marius R, Martin N, Jamieson T, Azad T, Diallo JS, Ilkow CS, Bell JC. Boulton S, et al. Among authors: azad t. Mol Ther Methods Clin Dev. 2023 Sep 16;31:101110. doi: 10.1016/j.omtm.2023.101110. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 37822719 Free PMC article.
Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development.
Boulton S, Crupi MJF, Singh S, Carter-Timofte ME, Azad T, Organ BC, He X, Gill R, Neault S, Jamieson T, Dave J, Kurmasheva N, Austin B, Petryk J, Singaravelu R, Huang BZ, Franco N, Babu K, Parks RJ, Ilkow CS, Olagnier D, Bell JC. Boulton S, et al. Among authors: azad t. J Biol Chem. 2023 Jun;299(6):104749. doi: 10.1016/j.jbc.2023.104749. Epub 2023 Apr 24. J Biol Chem. 2023. PMID: 37100284 Free PMC article.
321 results