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Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids.
Stijlemans B, De Baetselier P, Van Molle I, Lecordier L, Hendrickx E, Romão E, Vincke C, Baetens W, Schoonooghe S, Hassanzadeh-Ghassabeh G, Korf H, Wallays M, Pinto Torres JE, Perez-Morga D, Brys L, Campetella O, Leguizamón MS, Claes M, Hendrickx S, Mabille D, Caljon G, Remaut H, Roelants K, Magez S, Van Ginderachter JA, De Trez C. Stijlemans B, et al. Among authors: claes m. Nat Commun. 2024 Feb 27;15(1):1779. doi: 10.1038/s41467-024-46067-4. Nat Commun. 2024. PMID: 38413606 Free PMC article.
Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.
Ilbeigi K, Mabille D, Matheeussen A, Hendrickx R, Claes M, Van Reet N, Anthonissen R, Hulpia F, Lin C, Maes L, Regnault C, Whitfield P, Roy R, Ungogo MA, Sterckx YG, De Winter H, Mertens B, Bundschuh M, De Koning HP, Van Calenbergh S, Caljon G. Ilbeigi K, et al. Among authors: claes m. ACS Infect Dis. 2025 Jan 10;11(1):131-143. doi: 10.1021/acsinfecdis.4c00472. Epub 2024 Dec 12. ACS Infect Dis. 2025. PMID: 39665421
A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death.
Van Dender C, Timmermans S, Paakinaho V, Vanderhaeghen T, Vandewalle J, Claes M, Garcia B, Roman B, De Waele J, Croubels S, De Bosscher K, Meuleman P, Herpain A, Palvimo JJ, Libert C. Van Dender C, et al. Among authors: claes m. EMBO Mol Med. 2024 Oct;16(10):2485-2515. doi: 10.1038/s44321-024-00130-1. Epub 2024 Sep 11. EMBO Mol Med. 2024. PMID: 39261648 Free PMC article.
A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome.
Ahuja K, Vandenabeele M, Nami F, Lefevere E, Van Hoecke J, Bergmans S, Claes M, Vervliet T, Neyrinck K, Burg T, De Herdt D, Bhaskar P, Zhu Y, Looser ZJ, Loncke J, Gsell W, Plaas M, Agostinis P, Swinnen JV, Van Den Bosch L, Bultynck G, Saab AS, Wolfs E, Chai YC, Himmelreich U, Verfaillie C, Moons L, De Groef L. Ahuja K, et al. Among authors: claes m. Acta Neuropathol Commun. 2024 Aug 28;12(1):140. doi: 10.1186/s40478-024-01851-7. Acta Neuropathol Commun. 2024. PMID: 39198924 Free PMC article.
Genetic mapping across autoimmune diseases reveals shared associations and mechanisms.
Lincoln MR, Connally N, Axisa PP, Gasperi C, Mitrovic M, van Heel D, Wijmenga C, Withoff S, Jonkers IH, Padyukov L; International Multiple Sclerosis Genetics Consortium; Rich SS, Graham RR, Gaffney PM, Langefeld CD, Vyse TJ, Hafler DA, Chun S, Sunyaev SR, Cotsapas C. Lincoln MR, et al. Nat Genet. 2024 May;56(5):838-845. doi: 10.1038/s41588-024-01732-8. Epub 2024 May 13. Nat Genet. 2024. PMID: 38741015
68 results