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Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma.
Wong RLY, Wong MRE, Kuick CH, Saffari SE, Wong MK, Tan SH, Merchant K, Chang KTE, Thangavelu M, Periyasamy G, Chen ZX, Iyer P, Tan EEK, Soh SY, Iyer NG, Fan Q, Loh AHP. Wong RLY, et al. Among authors: iyer ng, iyer p. Front Oncol. 2021 Oct 14;11:709525. doi: 10.3389/fonc.2021.709525. eCollection 2021. Front Oncol. 2021. PMID: 34722256 Free PMC article.
Neuroblastoma patient-derived cultures are enriched for a mesenchymal gene signature and reflect individual drug response.
Hee E, Wong MK, Tan SH, Choo Z, Kuick CH, Ling S, Yong MH, Jain S, Lian DWQ, Ng EHQ, Yong YFL, Ren MH, Syed Sulaiman N, Low SYY, Chua YW, Syed MF, Lim TKH, Soh SY, Iyer P, Seng MSF, Lam JCM, Tan EEK, Chan MY, Tan AM, Chen Y, Chen Z, Chang KTE, Loh AHP. Hee E, et al. Among authors: iyer p. Cancer Sci. 2020 Oct;111(10):3780-3792. doi: 10.1111/cas.14610. Epub 2020 Aug 28. Cancer Sci. 2020. PMID: 32777141 Free PMC article.
930 results