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A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model.
Prakash S, Dhanushkodi NR, Singer M, Quadiri A, Zayou L, Vahed H, Coulon PG, Ibraim IC, Tafoya C, Hitchcock L, Landucci G, Forthal DN, El Babsiri A, Tifrea DF, Figueroa CJ, Nesburn AB, Kuppermann BD, Gil D, Jones TM, Ulmer JB, BenMohamed L. Prakash S, et al. Among authors: landucci g. bioRxiv [Preprint]. 2024 Feb 15:2024.02.14.580225. doi: 10.1101/2024.02.14.580225. bioRxiv. 2024. PMID: 38405942 Free PMC article. Preprint.
Heavily glycosylated, highly fit SIVMne variants continue to diversify and undergo selection after transmission to a new host and they elicit early antibody dependent cellular responses but delayed neutralizing antibody responses.
Eastman D, Piantadosi A, Wu X, Forthal DN, Landucci G, Kimata JT, Overbaugh J. Eastman D, et al. Among authors: landucci g. Virol J. 2008 Aug 4;5:90. doi: 10.1186/1743-422X-5-90. Virol J. 2008. PMID: 18680596 Free PMC article.
84 results