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Page 1
Hepatic bile acid accretion correlates with cholestatic liver injury and therapeutic response in Cyp2c70 knockout mice with a humanized bile acid composition.
Klindt C, Truong JK, Bennett AL, Pachura KJ, Herebian D, Mayatepek E, Luedde T, Ebert M, Karpen SJ, Dawson PA. Klindt C, et al. Among authors: karpen sj. Am J Physiol Gastrointest Liver Physiol. 2024 Dec 1;327(6):G789-G809. doi: 10.1152/ajpgi.00129.2024. Epub 2024 Oct 1. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 39350733
Quantifying Forms and Functions of Enterohepatic Bile Acid Pools in Mice.
Sudo K, Delmas-Eliason A, Soucy S, Barrack KE, Liu J, Balasubramanian A, Shu CJ, James MJ, Hegner CL, Dionne HD, Rodriguez-Palacios A, Krause HM, O'Toole GA, Karpen SJ, Dawson PA, Schultz D, Sundrud MS. Sudo K, et al. Among authors: karpen sj. Cell Mol Gastroenterol Hepatol. 2024;18(6):101392. doi: 10.1016/j.jcmgh.2024.101392. Epub 2024 Aug 22. Cell Mol Gastroenterol Hepatol. 2024. PMID: 39179177 Free PMC article.
BiliQML: a supervised machine-learning model to quantify biliary forms from digitized whole slide liver histopathological images.
Hellen DJ, Fay ME, Lee DH, Klindt-Morgan C, Bennett A, Pachura KJ, Grakoui A, Huppert SS, Dawson PA, Lam WA, Karpen SJ. Hellen DJ, et al. Among authors: karpen sj. Am J Physiol Gastrointest Liver Physiol. 2024 Jul 1;327(1):G1-G15. doi: 10.1152/ajpgi.00058.2024. Epub 2024 Apr 23. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 38651949
Diagnostic accuracy of serum matrix metalloproteinase-7 as a biomarker of biliary atresia in a large North American cohort.
Pandurangi S, Mourya R, Nalluri S, Fei L, Dong S, Harpavat S, Guthery SL, Molleston JP, Rosenthal P, Sokol RJ, Wang KS, Ng V, Alonso EM, Hsu EK, Karpen SJ, Loomes KM, Magee JC, Shneider BL, Horslen SP, Teckman JH, Bezerra JA; Childhood Liver Disease Research Network. Pandurangi S, et al. Among authors: karpen sj. Hepatology. 2024 Jul 1;80(1):152-162. doi: 10.1097/HEP.0000000000000827. Epub 2024 Mar 6. Hepatology. 2024. PMID: 38446707 Free PMC article.
Quantifying forms and functions of intestinal bile acid pools in mice.
Sudo K, Delmas-Eliason A, Soucy S, Barrack KE, Liu J, Balasubramanian A, Shu CJ, James M, Hegner CL, Dionne HD, Rodriguez-Palacios A, Krause H, O'Toole GA, Karpen SJ, Dawson PA, Schultz D, Sundrud MS. Sudo K, et al. Among authors: karpen sj. bioRxiv [Preprint]. 2024 Feb 18:2024.02.16.580658. doi: 10.1101/2024.02.16.580658. bioRxiv. 2024. Update in: Cell Mol Gastroenterol Hepatol. 2024;18(6):101392. doi: 10.1016/j.jcmgh.2024.101392 PMID: 38405928 Free PMC article. Updated. Preprint.
Event-free survival of maralixibat-treated patients with Alagille syndrome compared to a real-world cohort from GALA.
Hansen BE, Vandriel SM, Vig P, Garner W, Mogul DB, Loomes KM, Piccoli DA, Rand EB, Jankowska I, Czubkowski P, Gliwicz-Miedzińska D, Gonzales EM, Jacquemin E, Bouligand J, D'Antiga L, Nicastro E, Arnell H, Fischler B, Sokal É, Demaret T, Siew S, Stormon M, Karpen SJ, Romero R, Ebel NH, Feinstein JA, Roberts AJ, Evans HM, Sundaram SS, Chaidez A, Hardikar W, Shankar S, Fischer RT, Lacaille F, Debray D, Lin HC, Jensen MK, Jaramillo C, Karthikeyan P, Indolfi G, Verkade HJ, Larson-Nath C, Quiros-Tejeira RE, Valentino PL, Rogalidou M, Dezsőfi A, Squires JE, Schwarz K, Calvo PL, Bernabeu JQ, Zizzo AN, Nebbia G, Bulut P, Santos-Silva E, Fawaz R, Nastasio S, Karnsakul W, Tamara ML, Busoms CM, Kelly DA, Sandahl TD, Jimenez-Rivera C, Banales JM, Mujawar Q, Li LT, She H, Wang JS, Kim KM, Oh SH, Sanchez MC, Cavalieri ML, Lee WS, Hajinicolaou C, Lertudomphonwanit C, Waisbourd-Zinman O, Arikan C, Alam S, Carvalho E, Melere M, Eshun J, Önal Z, Desai DM, Wiecek S, Pinto RB, Wolters VM, Garcia J, Beretta M, Kerkar N, Brecelj J, Rock N, Lurz E, Blondet N, Shah U, Thompson RJ, Kamath BM; Global ALagille Alliance (GALA) Study Group. Hansen BE, et al. Among authors: karpen sj. Hepatology. 2024 Jun 1;79(6):1279-1292. doi: 10.1097/HEP.0000000000000727. Epub 2023 Dec 25. Hepatology. 2024. PMID: 38146932 Free PMC article.
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG. Ghallab A, et al. Among authors: karpen sj. J Hepatol. 2024 Feb;80(2):268-281. doi: 10.1016/j.jhep.2023.10.035. Epub 2023 Nov 7. J Hepatol. 2024. PMID: 37939855 Free PMC article.
188 results