Saxena K - Search Results

1

Back-pocket optimization of 2-aminopyrimidine-based macrocycles leads to potent dual EPHA2/GAK kinase inhibitors with antiviral activity.

Gerninghaus J, Zhubi R, Krämer A, Karim M, Tran DHN, Joerger AC, Schreiber C, Berger LM, Berger BT, Ehret TAL, Elson L, Lenz C, Saxena K, Müller S, Einav S, Knapp S, Hanke T. Gerninghaus J, et al. Among authors: saxena k. bioRxiv [Preprint]. 2024 Feb 18:2024.02.18.580805. doi: 10.1101/2024.02.18.580805. bioRxiv. 2024. Update in: J Med Chem. 2024 Aug 8;67(15):12534-12552. doi: 10.1021/acs.jmedchem.4c00411 PMID: 38405908 Free PMC article. Updated. Preprint.

2

A C-Degron Structure-Based Approach for the Development of Ligands Targeting the E3 Ligase TRIM7.

Muñoz Sosa CJ, Lenz C, Hamann A, Farges F, Dopfer J, Krämer A, Cherkashyna V, Tarnovskiy A, Moroz YS, Proschak E, Němec V, Müller S, Saxena K, Knapp S. Muñoz Sosa CJ, et al. Among authors: saxena k. ACS Chem Biol. 2024 Jul 19;19(7):1638-1647. doi: 10.1021/acschembio.4c00301. Epub 2024 Jun 27. ACS Chem Biol. 2024. PMID: 38934237

3

Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors.

Gerninghaus J, Zhubi R, Krämer A, Karim M, Tran DHN, Joerger AC, Schreiber C, Berger LM, Berger BT, Ehret TAL, Elson L, Lenz C, Saxena K, Müller S, Einav S, Knapp S, Hanke T. Gerninghaus J, et al. Among authors: saxena k. J Med Chem. 2024 Aug 8;67(15):12534-12552. doi: 10.1021/acs.jmedchem.4c00411. Epub 2024 Jul 19. J Med Chem. 2024. PMID: 39028937

4

Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization.

Schwalm MP, Krämer A, Dölle A, Weckesser J, Yu X, Jin J, Saxena K, Knapp S. Schwalm MP, et al. Among authors: saxena k. Cell Chem Biol. 2023 Jul 20;30(7):753-765.e8. doi: 10.1016/j.chembiol.2023.06.002. Epub 2023 Jun 23. Cell Chem Biol. 2023. PMID: 37354907 Free article.

5

Erratum for Kar et al., "Cimicifugin, a broad-spectrum inhibitor of Theileria annulata and Plasmodium falciparum CDK7".

Kar PP, Araveti PB, Saxena K, Borah A, Sijwali P, Srivastava A. Kar PP, et al. Among authors: saxena k. Antimicrob Agents Chemother. 2025 Jan 24:e0178224. doi: 10.1128/aac.01782-24. Online ahead of print. Antimicrob Agents Chemother. 2025. PMID: 39853122 Free article. No abstract available.

6

Correction to: Recovery from HPV vaccination deficits caused by the COVID-19 pandemic in Germany: a modeling study of catch-up HPV vaccination among adolescent girls.

Saxena K, Wähner C, Luzak A, Reuter T, Morais E, Chen YT. Saxena K, et al. Eur J Pediatr. 2025 Jan 7;184(1):118. doi: 10.1007/s00431-024-05940-6. Eur J Pediatr. 2025. PMID: 39762470 Free PMC article. No abstract available.

7

Biomarkers of Parkinson's Disease.

Sahai A, Saxena K. Sahai A, et al. Among authors: saxena k. Ann Neurosci. 2024 Dec 19:09727531241301878. doi: 10.1177/09727531241301878. Online ahead of print. Ann Neurosci. 2024. PMID: 39712433 Free PMC article. Review.

8

BH3 Mimetics Augment Cytotoxic T Cell Killing of Acute Myeloid Leukemia via Mitochondrial Apoptotic Mechanism.

Yee C, Saxena K, Ryu E, Hung SH, Singh S, Zhang Q, Zeng Z, Wang Z, Konopleva M. Yee C, et al. Among authors: saxena k. Res Sq [Preprint]. 2024 Dec 9:rs.3.rs-5307127. doi: 10.21203/rs.3.rs-5307127/v1. Res Sq. 2024. PMID: 39711535 Free PMC article. Preprint.

9

Trends in adolescent and adult vaccination in pharmacy and medical settings in the United States, 2018-2024: a database study.

Zheng Y, Wang D, Chen YT, Saxena K, Bencina G, Eiden AL. Zheng Y, et al. Among authors: saxena k. Expert Rev Vaccines. 2025 Dec;24(1):53-66. doi: 10.1080/14760584.2024.2441255. Epub 2024 Dec 22. Expert Rev Vaccines. 2025. PMID: 39676290 Free article.

10

Navigating regulatory and policy challenges for AI enabled combination devices.

Santra S, Kukreja P, Saxena K, Gandhi S, Singh OV. Santra S, et al. Among authors: saxena k. Front Med Technol. 2024 Nov 28;6:1473350. doi: 10.3389/fmedt.2024.1473350. eCollection 2024. Front Med Technol. 2024. PMID: 39669903 Free PMC article. Review.

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