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Supramolecular assembly of micellar aggregates is the basis of low endotoxin recovery (LER) in a drug formulation that can be resolved by a whole blood assay.
Schromm AB, Correa W, Gisch N, Steiniger F, Richter W, Martinez-de-Tejada G, Brandenburg K, von Wintzingerode F. Schromm AB, et al. Among authors: correa w. Biomed Pharmacother. 2024 Apr;173:116286. doi: 10.1016/j.biopha.2024.116286. Epub 2024 Feb 24. Biomed Pharmacother. 2024. PMID: 38401515 Free article.
LPS-neutralizing peptides reduce outer membrane vesicle-induced inflammatory responses.
Pfalzgraff A, Correa W, Heinbockel L, Schromm AB, Lübow C, Gisch N, Martinez-de-Tejada G, Brandenburg K, Weindl G. Pfalzgraff A, et al. Among authors: correa w. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1503-1513. doi: 10.1016/j.bbalip.2019.05.018. Epub 2019 Jun 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31163264
An update on endotoxin neutralization strategies in Gram-negative bacterial infections.
Brandenburg K, Schromm AB, Weindl G, Heinbockel L, Correa W, Mauss K, Martinez de Tejada G, Garidel P. Brandenburg K, et al. Among authors: correa w. Expert Rev Anti Infect Ther. 2021 Apr;19(4):495-517. doi: 10.1080/14787210.2021.1834847. Epub 2020 Nov 19. Expert Rev Anti Infect Ther. 2021. PMID: 33210958 Review.
Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides.
Martinez de Tejada G, Heinbockel L, Ferrer-Espada R, Heine H, Alexander C, Bárcena-Varela S, Goldmann T, Correa W, Wiesmüller KH, Gisch N, Sánchez-Gómez S, Fukuoka S, Schürholz T, Gutsmann T, Brandenburg K. Martinez de Tejada G, et al. Among authors: correa w. Sci Rep. 2015 Sep 22;5:14292. doi: 10.1038/srep14292. Sci Rep. 2015. PMID: 26390973 Free PMC article.
83 results