Franco LS - Search Results

1

Stereochemical insights into β-amino-N-acylhydrazones and their impact on DPP-4 inhibition.

Reina E, Franco LS, Carneiro TR, Barreiro EJ, Lima LM. Reina E, et al. Among authors: franco ls. RSC Adv. 2024 Feb 22;14(10):6617-6626. doi: 10.1039/d4ra00450g. eCollection 2024 Feb 21. RSC Adv. 2024. PMID: 38390500 Free PMC article.

2

Chemical Intuition in Drug Design and Discovery.

Pedreira JGB, Franco LS, Barreiro EJ. Pedreira JGB, et al. Among authors: franco ls. Curr Top Med Chem. 2019;19(19):1679-1693. doi: 10.2174/1568026619666190620144142. Curr Top Med Chem. 2019. PMID: 31258088 Review.

3

Novel phosphatidylinositol 4-kinases III beta (PI4KIIIβ) inhibitors discovered by virtual screening using free energy models.

Colodette NM, Franco LS, Maia RC, Fokoue HH, Sant'Anna CMR, Barreiro EJ. Colodette NM, et al. Among authors: franco ls. J Comput Aided Mol Des. 2020 Oct;34(10):1091-1103. doi: 10.1007/s10822-020-00327-9. Epub 2020 Jun 30. J Comput Aided Mol Des. 2020. PMID: 32601839 Free PMC article.

4

Identification of LASSBio-1945 as an inhibitor of SARS-CoV-2 main protease (M^PRO) through in silico screening supported by molecular docking and a fragment-based pharmacophore model.

Franco LS, Maia RC, Barreiro EJ. Franco LS, et al. RSC Med Chem. 2020 Nov 2;12(1):110-119. doi: 10.1039/d0md00282h. eCollection 2021 Jan 1. RSC Med Chem. 2020. PMID: 34046603 Free PMC article.

5

Discovery of Putative Dual Inhibitor of Tubulin and EGFR by Phenotypic Approach on LASSBio-1586 Homologs.

Barbosa G, Gelves LGV, Costa CMX, Franco LS, Lima JAL, Aparecida-Silva C, Teixeira JD, Mermelstein CDS, Barreiro EJ, Lima LM. Barbosa G, et al. Among authors: franco ls. Pharmaceuticals (Basel). 2022 Jul 23;15(8):913. doi: 10.3390/ph15080913. Pharmaceuticals (Basel). 2022. PMID: 35893736 Free PMC article.

6

Regioselective Nucleophilic Aromatic Substitution: Theoretical and Experimental Insights into 4-Aminoquinazoline Synthesis as a Privileged Structure in Medicinal Chemistry.

Barbosa MLC, Pinheiro PSM, Alves da Conceição R, Pires JR, Franco LS, Sant'Anna CMR, Barreiro EJ, Lima LM. Barbosa MLC, et al. Among authors: franco ls. Molecules. 2024 Dec 20;29(24):6021. doi: 10.3390/molecules29246021. Molecules. 2024. PMID: 39770108 Free PMC article.

7

The Magic Methyl and Its Tricks in Drug Discovery and Development.

Pinheiro PSM, Franco LS, Fraga CAM. Pinheiro PSM, et al. Among authors: franco ls. Pharmaceuticals (Basel). 2023 Aug 15;16(8):1157. doi: 10.3390/ph16081157. Pharmaceuticals (Basel). 2023. PMID: 37631072 Free PMC article. Review.

8

Molecular hybridization: a powerful tool for multitarget drug discovery.

de Sena Murteira Pinheiro P, Franco LS, Montagnoli TL, Fraga CAM. de Sena Murteira Pinheiro P, et al. Among authors: franco ls. Expert Opin Drug Discov. 2024 Apr;19(4):451-470. doi: 10.1080/17460441.2024.2322990. Epub 2024 Mar 8. Expert Opin Drug Discov. 2024. PMID: 38456452 Review.

9

Remapping the Chemical Space and the Pharmacological Space of Drugs: What Can We Expect from the Road Ahead?

Franco LS, de Jesus BDSM, Pinheiro PSM, Fraga CAM. Franco LS, et al. Pharmaceuticals (Basel). 2024 Jun 6;17(6):742. doi: 10.3390/ph17060742. Pharmaceuticals (Basel). 2024. PMID: 38931408 Free PMC article.

10

Detection of high-risk Avian Pathogenic Escherichia coli (APEC) isolated from broilers in São Paulo, Brazil.

Barbosa FB, Santos BQ, Rocha VGP, Franco LS, Saidenberg ABS, Moreno AM, Knöbl T. Barbosa FB, et al. Among authors: franco ls. Braz J Microbiol. 2023 Sep;54(3):2471-2475. doi: 10.1007/s42770-023-01023-0. Epub 2023 Jun 21. Braz J Microbiol. 2023. PMID: 37341945 Free PMC article.

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