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Page 1
A panel-based mutational signature of homologous recombination deficiency associates with response to PARP inhibition in metastatic castration-resistant prostate cancer.
Boiarsky D, Tewari AK, Gulhan DC, Bakouny Z, Ananda G, Savignano H, Lakshminarayanan G, McClure HM, Silver R, Choueiri TK, Taplin ME, Park PJ, Berchuck JE. Boiarsky D, et al. Among authors: gulhan dc. Prostate. 2024 Dec;84(16):1479-1489. doi: 10.1002/pros.24788. Epub 2024 Sep 9. Prostate. 2024. PMID: 39252459
Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns.
Watson EV, Lee JJ, Gulhan DC, Melloni GEM, Venev SV, Magesh RY, Frederick A, Chiba K, Wooten EC, Naxerova K, Dekker J, Park PJ, Elledge SJ. Watson EV, et al. Among authors: gulhan dc. Nat Genet. 2024 May;56(5):900-912. doi: 10.1038/s41588-024-01665-2. Epub 2024 Feb 22. Nat Genet. 2024. PMID: 38388848 Free PMC article.
Accurate and sensitive mutational signature analysis with MuSiCal.
Jin H, Gulhan DC, Geiger B, Ben-Isvy D, Geng D, Ljungström V, Park PJ. Jin H, et al. Among authors: gulhan dc. Nat Genet. 2024 Mar;56(3):541-552. doi: 10.1038/s41588-024-01659-0. Epub 2024 Feb 15. Nat Genet. 2024. PMID: 38361034 Free PMC article.
A Panel-Based Mutational Signature of Mismatch Repair Deficiency is Associated With Durable Response to Pembrolizumab in Metastatic Castration-Resistant Prostate Cancer.
Boiarsky D, Gulhan DC, Savignano H, Lakshminarayanan G, McClure HM, Silver R, Hirsch MS, Sholl LM, Choudhury AD, Ananda G, Park PJ, Tewari AK, Berchuck JE. Boiarsky D, et al. Among authors: gulhan dc. Clin Genitourin Cancer. 2024 Apr;22(2):558-568.e3. doi: 10.1016/j.clgc.2024.01.011. Epub 2024 Jan 20. Clin Genitourin Cancer. 2024. PMID: 38342659 Free article.
Predicting response to immune checkpoint blockade therapy among mismatch repair-deficient patients using mutational signatures.
Gulhan DC, Viswanadham V, Muyas F, Jin H, Foote MB, Lee JJ, Barras D, Jung YL, Ljungstrom V, Rousseau B, Galor A, Diplas BH, Maron SB, Cleary JM, Cortés-Ciriano I, Park PJ. Gulhan DC, et al. medRxiv [Preprint]. 2024 Jan 21:2024.01.19.24301236. doi: 10.1101/2024.01.19.24301236. medRxiv. 2024. PMID: 38293061 Free PMC article. Preprint.
Hyper-Dependence on NHEJ Enables Synergy between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma.
Marino-Enriquez A, Novotny JP, Gulhan DC, Klooster I, Tran AV, Kasbo M, Lundberg MZ, Ou WB, Tao DL, Pilco-Janeta DF, Mao VY, Zenke FT, Leeper BA, Gokhale PC, Cowley GS, Baker LH, Ballman KV, Root DE, Albers J, Park PJ, George S, Fletcher JA. Marino-Enriquez A, et al. Among authors: gulhan dc. Clin Cancer Res. 2023 Dec 15;29(24):5128-5139. doi: 10.1158/1078-0432.CCR-23-0998. Clin Cancer Res. 2023. PMID: 37773632 Free PMC article.
Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing.
Rodin RE, Dou Y, Kwon M, Sherman MA, D'Gama AM, Doan RN, Rento LM, Girskis KM, Bohrson CL, Kim SN, Nadig A, Luquette LJ, Gulhan DC; Brain Somatic Mosaicism Network; Park PJ, Walsh CA. Rodin RE, et al. Among authors: gulhan dc. Nat Neurosci. 2023 Oct;26(10):1833. doi: 10.1038/s41593-023-01437-x. Nat Neurosci. 2023. PMID: 37644260 No abstract available.
24 results