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Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo.
Mol Cell. 2024 Apr 4;84(7):1271-1289.e12. doi: 10.1016/j.molcel.2024.01.026. Epub 2024 Feb 21.
Mol Cell. 2024.
PMID: 38387462
3D genome organization around nuclear speckles drives mRNA splicing efficiency.
Bhat P, Chow A, Emert B, Ettlin O, Quinodoz SA, Takei Y, Huang W, Blanco MR, Guttman M.
Bhat P, et al. Among authors: ettlin o.
bioRxiv [Preprint]. 2023 Jan 4:2023.01.04.522632. doi: 10.1101/2023.01.04.522632.
bioRxiv. 2023.
Update in:
Nature. 2024 May;629(8014):1165-1173. doi: 10.1038/s41586-024-07429-6
PMID: 36711853
Free PMC article.
Updated.
Preprint.
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ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements.
Perez AA, Goronzy IN, Blanco MR, Yeh BT, Guo JK, Lopes CS, Ettlin O, Burr A, Guttman M.
Perez AA, et al. Among authors: ettlin o.
Nat Genet. 2024 Dec;56(12):2827-2841. doi: 10.1038/s41588-024-02000-5. Epub 2024 Nov 25.
Nat Genet. 2024.
PMID: 39587360
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Genome organization around nuclear speckles drives mRNA splicing efficiency.
Bhat P, Chow A, Emert B, Ettlin O, Quinodoz SA, Strehle M, Takei Y, Burr A, Goronzy IN, Chen AW, Huang W, Ferrer JLM, Soehalim E, Goh ST, Chari T, Sullivan DK, Blanco MR, Guttman M.
Bhat P, et al. Among authors: ettlin o.
Nature. 2024 May;629(8014):1165-1173. doi: 10.1038/s41586-024-07429-6. Epub 2024 May 8.
Nature. 2024.
PMID: 38720076
Free PMC article.
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