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Key mutations in the C-terminus of the HBV surface glycoprotein correlate with lower HBsAg levels in vivo, hinder HBsAg secretion in vitro and reduce HBsAg structural stability in the setting of HBeAg-negative chronic HBV genotype-D infection.
Salpini R, Battisti A, Piermatteo L, Carioti L, Anastasiou OE, Gill US, Di Carlo D, Colagrossi L, Duca L, Bertoli A, La Rosa KY, Fabeni L, Iuvara A, Malagnino V, Cerva C, Lichtner M, Mastroianni CM, De Sanctis GM, Paoloni M, Marignani M, Pasquazzi C, Iapadre N, Parruti G, Vecchiet J, Sarmati L, Andreoni M, Angelico M, Grelli S, T Kennedy P, Verheyen J, Aquaro S, Silberstein FC, Perno CF, Svicher V. Salpini R, et al. Among authors: gill us. Emerg Microbes Infect. 2020 Dec;9(1):928-939. doi: 10.1080/22221751.2020.1757998. Emerg Microbes Infect. 2020. PMID: 32312174 Free PMC article.
Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.
Pallett LJ, Gill US, Quaglia A, Sinclair LV, Jover-Cobos M, Schurich A, Singh KP, Thomas N, Das A, Chen A, Fusai G, Bertoletti A, Cantrell DA, Kennedy PT, Davies NA, Haniffa M, Maini MK. Pallett LJ, et al. Among authors: gill us. Nat Med. 2015 Jun;21(6):591-600. doi: 10.1038/nm.3856. Epub 2015 May 11. Nat Med. 2015. PMID: 25962123 Free PMC article.
86 results