Bradner JE - Search Results

1

Author Correction: An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.

Souroullas GP, Jeck WR, Parker JS, Simon JM, Liu JY, Paulk J, Xiong J, Clark KS, Fedoriw Y, Qi J, Burd CE, Bradner JE, Sharpless NE. Souroullas GP, et al. Among authors: bradner je. Nat Med. 2024 Jun;30(6):1784. doi: 10.1038/s41591-024-02867-1. Nat Med. 2024. PMID: 38383796 No abstract available.

2

BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia.

Ott CJ, Kopp N, Bird L, Paranal RM, Qi J, Bowman T, Rodig SJ, Kung AL, Bradner JE, Weinstock DM. Ott CJ, et al. Among authors: bradner je. Blood. 2012 Oct 4;120(14):2843-52. doi: 10.1182/blood-2012-02-413021. Epub 2012 Aug 17. Blood. 2012. PMID: 22904298 Free PMC article.

3

Genome-wide localization of small molecules.

Anders L, Guenther MG, Qi J, Fan ZP, Marineau JJ, Rahl PB, Lovén J, Sigova AA, Smith WB, Lee TI, Bradner JE, Young RA. Anders L, et al. Among authors: bradner je. Nat Biotechnol. 2014 Jan;32(1):92-6. doi: 10.1038/nbt.2776. Epub 2013 Dec 15. Nat Biotechnol. 2014. PMID: 24336317 Free PMC article.

4

Targeting STAT5 in hematologic malignancies through inhibition of the bromodomain and extra-terminal (BET) bromodomain protein BRD2.

Liu S, Walker SR, Nelson EA, Cerulli R, Xiang M, Toniolo PA, Qi J, Stone RM, Wadleigh M, Bradner JE, Frank DA. Liu S, et al. Among authors: bradner je. Mol Cancer Ther. 2014 May;13(5):1194-205. doi: 10.1158/1535-7163.MCT-13-0341. Epub 2014 Jan 16. Mol Cancer Ther. 2014. PMID: 24435449 Free PMC article.

5

Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.

Tang Y, Gholamin S, Schubert S, Willardson MI, Lee A, Bandopadhayay P, Bergthold G, Masoud S, Nguyen B, Vue N, Balansay B, Yu F, Oh S, Woo P, Chen S, Ponnuswami A, Monje M, Atwood SX, Whitson RJ, Mitra S, Cheshier SH, Qi J, Beroukhim R, Tang JY, Wechsler-Reya R, Oro AE, Link BA, Bradner JE, Cho YJ. Tang Y, et al. Among authors: bradner je. Nat Med. 2014 Jul;20(7):732-40. doi: 10.1038/nm.3613. Epub 2014 Jun 29. Nat Med. 2014. PMID: 24973920 Free PMC article.

6

Acetylation site specificities of lysine deacetylase inhibitors in human cells.

Schölz C, Weinert BT, Wagner SA, Beli P, Miyake Y, Qi J, Jensen LJ, Streicher W, McCarthy AR, Westwood NJ, Lain S, Cox J, Matthias P, Mann M, Bradner JE, Choudhary C. Schölz C, et al. Among authors: bradner je. Nat Biotechnol. 2015 Apr;33(4):415-23. doi: 10.1038/nbt.3130. Epub 2015 Mar 9. Nat Biotechnol. 2015. PMID: 25751058

7

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.

Chen CW, Koche RP, Sinha AU, Deshpande AJ, Zhu N, Eng R, Doench JG, Xu H, Chu SH, Qi J, Wang X, Delaney C, Bernt KM, Root DE, Hahn WC, Bradner JE, Armstrong SA. Chen CW, et al. Among authors: bradner je. Nat Med. 2015 Apr;21(4):335-43. doi: 10.1038/nm.3832. Epub 2015 Mar 30. Nat Med. 2015. PMID: 25822366 Free PMC article.

8

DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation.

Winter GE, Buckley DL, Paulk J, Roberts JM, Souza A, Dhe-Paganon S, Bradner JE. Winter GE, et al. Among authors: bradner je. Science. 2015 Jun 19;348(6241):1376-81. doi: 10.1126/science.aab1433. Epub 2015 May 21. Science. 2015. PMID: 25999370 Free PMC article.

9

Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6.

Hu YJ, Belaghzal H, Hsiao WY, Qi J, Bradner JE, Guertin DA, Sif S, Imbalzano AN. Hu YJ, et al. Among authors: bradner je. Nucleic Acids Res. 2015 Sep 18;43(16):7790-804. doi: 10.1093/nar/gkv645. Epub 2015 Jun 27. Nucleic Acids Res. 2015. PMID: 26117538 Free PMC article.

10

Inhibitors of emerging epigenetic targets for cancer therapy: a patent review (2010-2014).

Tanaka M, Roberts JM, Qi J, Bradner JE. Tanaka M, et al. Among authors: bradner je. Pharm Pat Anal. 2015;4(4):261-84. doi: 10.4155/ppa.15.16. Pharm Pat Anal. 2015. PMID: 26174566 Review.

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