Frieß W - Search Results

1

Closing the Gap between Experiment and Simulation─A Holistic Study on the Complexation of Small Interfering RNAs with Polyethylenimine.

Binder J, Winkeljann J, Steinegger K, Trnovec L, Orekhova D, Zähringer J, Hörner A, Fell V, Tinnefeld P, Winkeljann B, Frieß W, Merkel OM. Binder J, et al. Among authors: friess w. Mol Pharm. 2024 May 6;21(5):2163-2175. doi: 10.1021/acs.molpharmaceut.3c00747. Epub 2024 Feb 19. Mol Pharm. 2024. PMID: 38373164 Free PMC article.

2

Interactions of hyaluronic Acid with the skin and implications for the dermal delivery of biomacromolecules.

Witting M, Boreham A, Brodwolf R, Vávrová K, Alexiev U, Friess W, Hedtrich S. Witting M, et al. Among authors: friess w. Mol Pharm. 2015 May 4;12(5):1391-401. doi: 10.1021/mp500676e. Epub 2015 Apr 22. Mol Pharm. 2015. PMID: 25871518

3

The Effect of Point Mutations on the Biophysical Properties of an Antimicrobial Peptide: Development of a Screening Protocol for Peptide Stability Screening.

Pohl C, Zalar M, Bialy IE, Indrakumar S, Peters GHJ, Friess W, Golovanov AP, Streicher WW, Noergaard A, Harris P. Pohl C, et al. Among authors: friess w. Mol Pharm. 2020 Sep 8;17(9):3298-3313. doi: 10.1021/acs.molpharmaceut.0c00406. Epub 2020 Aug 7. Mol Pharm. 2020. PMID: 32609526

4

Generation of mAb Variants with Less Attractive Self-Interaction but Preserved Target Binding by Well-Directed Mutation.

Domnowski M, Lo Presti K, Binder J, Reindl J, Lehmann L, Kummer F, Wolber M, Satzger M, Dehling M, Jaehrling J, Frieß W. Domnowski M, et al. Among authors: friess w. Mol Pharm. 2021 Jan 4;18(1):236-245. doi: 10.1021/acs.molpharmaceut.0c00848. Epub 2020 Dec 17. Mol Pharm. 2021. PMID: 33331157

5

Impact of crystalline and amorphous matrices on successful spray drying of siRNA polyplexes for inhalation of nano-in-microparticles.

Keil TW, Zimmermann C, Baldassi D, Adams F, Friess W, Mehta A, Merkel OM. Keil TW, et al. Among authors: friess w. Adv Ther (Weinh). 2021 May 7;4(6):2100073. doi: 10.1002/adtp.202100073. eCollection 2021 Jun. Adv Ther (Weinh). 2021. PMID: 34337144 Free PMC article.

6

Self-Interactions of Two Monoclonal Antibodies: Small-Angle X-ray Scattering, Light Scattering, and Coarse-Grained Modeling.

Mahapatra S, Polimeni M, Gentiluomo L, Roessner D, Frieß W, Peters GHJ, Streicher WW, Lund M, Harris P. Mahapatra S, et al. Among authors: friess w. Mol Pharm. 2022 Feb 7;19(2):508-519. doi: 10.1021/acs.molpharmaceut.1c00627. Epub 2021 Dec 23. Mol Pharm. 2022. PMID: 34939811

7

Evaluation of adsorption of DNA/PEI polyplexes to tubing materials.

Keil TWM, Deiringer N, Friess W, Merkel OM. Keil TWM, et al. Among authors: friess w. Eur J Pharm Biopharm. 2022 Oct;179:58-64. doi: 10.1016/j.ejpb.2022.08.014. Epub 2022 Aug 27. Eur J Pharm Biopharm. 2022. PMID: 36041597 Free PMC article.

8

Molecular Dynamics Study of Protein Aggregation at Moving Interfaces.

Sarter T, Friess W. Sarter T, et al. Among authors: friess w. Mol Pharm. 2024 Mar 4;21(3):1214-1221. doi: 10.1021/acs.molpharmaceut.3c00865. Epub 2024 Feb 7. Mol Pharm. 2024. PMID: 38321750

9

"The More, the Better?": The Impact of Sugar-to-Protein Molar Ratio in Freeze-Dried Monoclonal Antibody Formulations on Protein Stability.

Lo Presti K, Jégo M, Frieß W. Lo Presti K, et al. Among authors: friess w. Mol Pharm. 2024 Dec 2;21(12):6484-6490. doi: 10.1021/acs.molpharmaceut.4c01174. Epub 2024 Nov 20. Mol Pharm. 2024. PMID: 39564766

10

Insights into Folding and Molecular Environment of Lyophilized Proteins Using Pulsed Electron Paramagnetic Resonance Spectroscopy.

Isaev N, Lo Presti K, Frieß W. Isaev N, et al. Among authors: friess w. Mol Pharm. 2024 Dec 24. doi: 10.1021/acs.molpharmaceut.4c01008. Online ahead of print. Mol Pharm. 2024. PMID: 39718349

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