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Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1.
Khamrui S, Dodatko T, Wu R, Leandro J, Sabovic A, Violante S, Cross JR, Marsan E, Kumar K, DeVita RJ, Lazarus MB, Houten SM. Khamrui S, et al. Among authors: devita rj. bioRxiv [Preprint]. 2024 Feb 7:2024.02.07.578422. doi: 10.1101/2024.02.07.578422. bioRxiv. 2024. Update in: ACS Chem Biol. 2024 Jul 19;19(7):1544-1553. doi: 10.1021/acschembio.4c00204 PMID: 38370847 Free PMC article. Updated. Preprint.
Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation.
Stewart AF, Fulton SL, Durand-de Cuttoli R, Thompson RE, Chen PJ, Brindley E, Cetin B, Farrelly LA, Futamura R, Claypool S, Bastle RM, Di Salvo G, Peralta C, Molina H, Baljinnyam E, Marro SG, Russo SJ, DeVita RJ, Muir TW, Maze I. Stewart AF, et al. Among authors: devita rj. bioRxiv [Preprint]. 2024 Sep 24:2024.09.19.613951. doi: 10.1101/2024.09.19.613951. bioRxiv. 2024. PMID: 39345578 Free PMC article. Preprint.
Functional genomics pipeline identifies CRL4 inhibition for the treatment of ovarian cancer.
Claridge SE, Nath S, Baum A, Farias R, Cavallo JA, Rizvi NM, De Boni L, Park E, Granados GL, Hauesgen M, Fernandez-Rodriguez R, Kozan EN, Kanshin E, Huynh KQ, Chen PJ, Wu K, Ueberheide B, Mosquera JM, Hirsch FR, DeVita RJ, Elemento O, Pauli C, Pan ZQ, Hopkins BD. Claridge SE, et al. Among authors: devita rj. Clin Transl Med. 2025 Feb;15(2):e70078. doi: 10.1002/ctm2.70078. Clin Transl Med. 2025. PMID: 39856363 Free PMC article.
A Phase 1 single ascending dose study of pure oral harmine in healthy volunteers.
Ables JL, Israel L, Wood O, Govindarajulu U, Fremont RT, Banerjee R, Liu H, Cohen J, Wang P, Kumar K, Lu G, DeVita RJ, Garcia-Ocaña A, Murrough JW, Stewart AF. Ables JL, et al. Among authors: devita rj. J Psychopharmacol. 2024 Oct;38(10):911-923. doi: 10.1177/02698811241273772. Epub 2024 Sep 20. J Psychopharmacol. 2024. PMID: 39301926 Free PMC article. Clinical Trial.
Monoubiquitination empowers ubiquitin chain elongation.
Wu K, DeVita RJ, Pan ZQ. Wu K, et al. Among authors: devita rj. J Biol Chem. 2024 Mar;300(3):105753. doi: 10.1016/j.jbc.2024.105753. Epub 2024 Feb 13. J Biol Chem. 2024. PMID: 38354782 Free PMC article.
70 results