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Integrated NMR-crystallography-computational approach for molecular recognition studies of human Gαi3 protein by a small molecule inhibitor.
Ferreras-Gutiérrez M, Mínguez-Toral M, Ibáñez de Opakua A, Martín-Santamaría S, García-Marcos M, Medrano FJ, Blanco FJ. Ferreras-Gutiérrez M, et al. Among authors: garcia marcos m. Int J Biol Macromol. 2024 Dec 18;290:138977. doi: 10.1016/j.ijbiomac.2024.138977. Online ahead of print. Int J Biol Macromol. 2024. PMID: 39706421 Free article.
Direct interrogation of context-dependent GPCR activity with a universal biosensor platform.
Janicot R, Maziarz M, Park JC, Luebbers A, Green E, Zhao J, Philibert C, Zhang H, Layne MD, Wu JC, Garcia-Marcos M. Janicot R, et al. Among authors: garcia marcos m. bioRxiv [Preprint]. 2024 Jan 2:2024.01.02.573921. doi: 10.1101/2024.01.02.573921. bioRxiv. 2024. Update in: Cell. 2024 Mar 14;187(6):1527-1546.e25. doi: 10.1016/j.cell.2024.01.028 PMID: 38260348 Free PMC article. Updated. Preprint.
Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression.
Zhao J, DiGiacomo V, Ferreras-Gutierrez M, Dastjerdi S, de Opakua AI, Park JC, Luebbers A, Chen Q, Beeler A, Blanco FJ, Garcia-Marcos M. Zhao J, et al. bioRxiv [Preprint]. 2023 Feb 19:2023.02.18.529092. doi: 10.1101/2023.02.18.529092. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2213140120. doi: 10.1073/pnas.2213140120 PMID: 36824907 Free PMC article. Updated. Preprint.
109 results