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Page 1
Cell type-specific functions of Alzheimer's disease endocytic risk genes.
Maninger JK, Nowak K, Goberdhan S, O'Donoghue R, Connor-Robson N. Maninger JK, et al. Among authors: connor robson n. Philos Trans R Soc Lond B Biol Sci. 2024 Apr 8;379(1899):20220378. doi: 10.1098/rstb.2022.0378. Epub 2024 Feb 19. Philos Trans R Soc Lond B Biol Sci. 2024. PMID: 38368934 Free PMC article. Review.
Tau depletion in human neurons mitigates Aβ-driven toxicity.
Ng B, Vowles J, Bertherat F, Abey A, Kilfeather P, Beccano-Kelly D, Stefana MI, O'Brien DP, Bengoa-Vergniory N, Carling PJ, Todd JA, Caffrey TM, Connor-Robson N, Cowley SA, Wade-Martins R. Ng B, et al. Among authors: connor robson n. Mol Psychiatry. 2024 Jul;29(7):2009-2020. doi: 10.1038/s41380-024-02463-2. Epub 2024 Feb 15. Mol Psychiatry. 2024. PMID: 38361127 Free PMC article.
Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's.
Brimblecombe KR, Connor-Robson N, Bataille CJR, Roberts BM, Gracie C, O'Connor B, Te Water Naude R, Karthik G, Russell AJ, Wade-Martins R, Cragg SJ. Brimblecombe KR, et al. Among authors: connor robson n. Eur J Neurosci. 2024 Mar;59(6):1242-1259. doi: 10.1111/ejn.16180. Epub 2023 Nov 8. Eur J Neurosci. 2024. PMID: 37941514 Free PMC article.
Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson's disease models.
Williamson MG, Madureira M, McGuinness W, Heon-Roberts R, Mock ED, Naidoo K, Cramb KML, Caiazza MC, Malpartida AB, Lavelle M, Savory K, Humble SW, Patterson R, Davis JB, Connor-Robson N, Ryan BJ, Wade-Martins R. Williamson MG, et al. Among authors: connor robson n. Hum Mol Genet. 2023 Sep 5;32(18):2808-2821. doi: 10.1093/hmg/ddad102. Hum Mol Genet. 2023. PMID: 37384414 Free PMC article.
Assaying Microglia Functions In Vitro.
Maguire E, Connor-Robson N, Shaw B, O'Donoghue R, Stöberl N, Hall-Roberts H. Maguire E, et al. Among authors: connor robson n. Cells. 2022 Oct 28;11(21):3414. doi: 10.3390/cells11213414. Cells. 2022. PMID: 36359810 Free PMC article. Review.
β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins.
Ninkina N, Millership SJ, Peters OM, Connor-Robson N, Chaprov K, Kopylov AT, Montoya A, Kramer H, Withers DJ, Buchman VL. Ninkina N, et al. Among authors: connor robson n. J Biol Chem. 2021 Dec;297(6):101375. doi: 10.1016/j.jbc.2021.101375. Epub 2021 Nov 2. J Biol Chem. 2021. PMID: 34736896 Free PMC article.
Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol.
Threlfell S, Mohammadi AS, Ryan BJ, Connor-Robson N, Platt NJ, Anand R, Serres F, Sharp T, Bengoa-Vergniory N, Wade-Martins R, Ewing A, Cragg SJ, Brimblecombe KR. Threlfell S, et al. Among authors: connor robson n. Front Cell Neurosci. 2021 Apr 15;15:658244. doi: 10.3389/fncel.2021.658244. eCollection 2021. Front Cell Neurosci. 2021. PMID: 33935654 Free PMC article.
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease.
Bengoa-Vergniory N, Faggiani E, Ramos-Gonzalez P, Kirkiz E, Connor-Robson N, Brown LV, Siddique I, Li Z, Vingill S, Cioroch M, Cavaliere F, Threlfell S, Roberts B, Schrader T, Klärner FG, Cragg S, Dehay B, Bitan G, Matute C, Bezard E, Wade-Martins R. Bengoa-Vergniory N, et al. Among authors: connor robson n. Nat Commun. 2020 Sep 28;11(1):4885. doi: 10.1038/s41467-020-18689-x. Nat Commun. 2020. PMID: 32985503 Free PMC article.
27 results