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Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) - a promising target for the immunotherapy of cancer.
Lopez V, Schuh HJM, Mirza S, Vaaßen VJ, Schmidt MS, Sylvester K, Idris RM, Renn C, Schäkel L, Pelletier J, Sévigny J, Naggi A, Scheffler B, Lee SY, Bendas G, Müller CE. Lopez V, et al. Among authors: bendas g. Front Immunol. 2023 Aug 29;14:1173634. doi: 10.3389/fimmu.2023.1173634. eCollection 2023. Front Immunol. 2023. PMID: 37711611 Free PMC article.
Pyrazinyl-Substituted Aminoazoles as Covalent Inhibitors of Thrombin: Synthesis, Structure, and Anticoagulant Properties.
Imberg L, Siutkina AI, Erbacher C, Schmidt J, Broekmans DF, Ovsepyan RA, Daniliuc CG, Gonçalves de Oliveira E, Serafim MSM, O'Donoghue AJ, Pillaiyar T, Panteleev MA, Poso A, Kalinina SA, Bermúdez M, Nekipelov K, Bendas G, Karst U, Kalinin DV. Imberg L, et al. Among authors: bendas g. ACS Pharmacol Transl Sci. 2024 Dec 11;8(1):146-172. doi: 10.1021/acsptsci.4c00515. eCollection 2025 Jan 10. ACS Pharmacol Transl Sci. 2024. PMID: 39816788
Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
Sinatra L, Vogelmann A, Friedrich F, Tararina MA, Neuwirt E, Colcerasa A, König P, Toy L, Yesiloglu TZ, Hilscher S, Gaitzsch L, Papenkordt N, Zhai S, Zhang L, Romier C, Einsle O, Sippl W, Schutkowski M, Gross O, Bendas G, Christianson DW, Hansen FK, Jung M, Schiedel M. Sinatra L, et al. Among authors: bendas g. J Med Chem. 2023 Nov 9;66(21):14787-14814. doi: 10.1021/acs.jmedchem.3c01385. Epub 2023 Oct 30. J Med Chem. 2023. PMID: 37902787 Free PMC article.
The Role of CD36/GPIV in Platelet Biology.
Bendas G, Schlesinger M. Bendas G, et al. Semin Thromb Hemost. 2024 Mar;50(2):224-235. doi: 10.1055/s-0043-1768935. Epub 2023 May 16. Semin Thromb Hemost. 2024. PMID: 37192651 Review.
116 results