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Impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by BDNF downregulation contribute to cognitive dysfunction in mice induced by repeated neonatal exposure to ketamine.
Wan J, Ma L, Jiao X, Dong W, Lin J, Qiu Y, Wu W, Liu Q, Chen C, Huang H, Li S, Zheng H, Wu Y. Wan J, et al. Among authors: qiu y. CNS Neurosci Ther. 2024 Feb;30(2):e14604. doi: 10.1111/cns.14604. CNS Neurosci Ther. 2024. PMID: 38332635 Free PMC article.
Impaired synaptic plasticity and decreased glutamatergic neuron excitability induced by SIRT1/BDNF downregulation in the hippocampal CA1 region are involved in postoperative cognitive dysfunction.
Wu WF, Chen C, Lin JT, Jiao XH, Dong W, Wan J, Liu Q, Qiu YK, Sun A, Liu YQ, Jin CH, Huang H, Zheng H, Zhou CH, Wu YQ. Wu WF, et al. Cell Mol Biol Lett. 2024 May 23;29(1):79. doi: 10.1186/s11658-024-00595-5. Cell Mol Biol Lett. 2024. PMID: 38783169 Free PMC article.
Structure-Based Design of "Head-to-Tail" Macrocyclic PROTACs.
Li C, Chen Y, Huang W, Qiu Y, Huang S, Zhou Y, Zhou F, Xu J, Ren X, Zhang J, Wang Z, Ding M, Ding K. Li C, et al. Among authors: qiu y. JACS Au. 2024 Nov 21;4(12):4866-4882. doi: 10.1021/jacsau.4c00831. eCollection 2024 Dec 23. JACS Au. 2024. PMID: 39735913 Free PMC article.
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