Griffin MDW - Search Results

1

Craniosynostosis-associated variants in the IL-11R complex: new insights and questions.

Sims NA, Griffin MDW. Sims NA, et al. Among authors: griffin mdw. FEBS J. 2024 Apr;291(8):1663-1666. doi: 10.1111/febs.17078. Epub 2024 Feb 8. FEBS J. 2024. PMID: 38329021

2

The structure of the IL-11 signalling complex provides insight into receptor variants associated with craniosynostosis.

Sentosa DD, Metcalfe RD, Sims NA, Putoczki TL, Griffin MDW. Sentosa DD, et al. Among authors: griffin mdw. FEBS J. 2024 Oct 27. doi: 10.1111/febs.17307. Online ahead of print. FEBS J. 2024. PMID: 39462650

3

Identification of an amyloid fibril forming peptide comprising residues 46-59 of apolipoprotein A-I.

Wong YQ, Binger KJ, Howlett GJ, Griffin MD. Wong YQ, et al. FEBS Lett. 2012 Jun 21;586(13):1754-8. doi: 10.1016/j.febslet.2012.05.007. Epub 2012 May 15. FEBS Lett. 2012. PMID: 22609356 Free article.

4

Polymorphism in disease-related apolipoprotein C-II amyloid fibrils: a structural model for rod-like fibrils.

Zlatic CO, Mao Y, Todorova N, Mok YF, Howlett GJ, Yarovsky I, Gooley PR, Griffin MDW. Zlatic CO, et al. Among authors: griffin mdw. FEBS J. 2018 Aug;285(15):2799-2812. doi: 10.1111/febs.14517. Epub 2018 Jun 9. FEBS J. 2018. PMID: 29791776 Free article.

5

The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement.

Metcalfe RD, Aizel K, Zlatic CO, Nguyen PM, Morton CJ, Lio DS, Cheng HC, Dobson RCJ, Parker MW, Gooley PR, Putoczki TL, Griffin MDW. Metcalfe RD, et al. Among authors: griffin mdw. J Biol Chem. 2020 Jun 12;295(24):8285-8301. doi: 10.1074/jbc.RA119.012351. Epub 2020 Apr 24. J Biol Chem. 2020. PMID: 32332100 Free PMC article.

6

Emerging roles for the IL-6 family of cytokines in pancreatic cancer.

van Duijneveldt G, Griffin MDW, Putoczki TL. van Duijneveldt G, et al. Among authors: griffin mdw. Clin Sci (Lond). 2020 Aug 28;134(16):2091-2115. doi: 10.1042/CS20191211. Clin Sci (Lond). 2020. PMID: 32808663 Free PMC article. Review.

7

Emerging roles for IL-11 in inflammatory diseases.

Fung KY, Louis C, Metcalfe RD, Kosasih CC, Wicks IP, Griffin MDW, Putoczki TL. Fung KY, et al. Among authors: griffin mdw. Cytokine. 2022 Jan;149:155750. doi: 10.1016/j.cyto.2021.155750. Epub 2021 Oct 22. Cytokine. 2022. PMID: 34689057 Free article. Review.

8

Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant.

Metcalfe RD, Hanssen E, Fung KY, Aizel K, Kosasih CC, Zlatic CO, Doughty L, Morton CJ, Leis AP, Parker MW, Gooley PR, Putoczki TL, Griffin MDW. Metcalfe RD, et al. Among authors: griffin mdw. Nat Commun. 2023 Nov 20;14(1):7543. doi: 10.1038/s41467-023-42754-w. Nat Commun. 2023. PMID: 37985757 Free PMC article.

9

The relationship between oligomeric state and protein function.

Griffin MD, Gerrard JA. Griffin MD, et al. Adv Exp Med Biol. 2012;747:74-90. doi: 10.1007/978-1-4614-3229-6_5. Adv Exp Med Biol. 2012. PMID: 22949112 Review.

10

Heterochromatin protein 1 alpha (HP1α) undergoes a monomer to dimer transition that opens and compacts live cell genome architecture.

Lou J, Deng Q, Zhang X, Bell CC, Das AB, Bediaga NG, Zlatic CO, Johanson TM, Allan RS, Griffin MDW, Paradkar P, Harvey KF, Dawson MA, Hinde E. Lou J, et al. Among authors: griffin mdw. Nucleic Acids Res. 2024 Oct 14;52(18):10918-10933. doi: 10.1093/nar/gkae720. Nucleic Acids Res. 2024. PMID: 39193905 Free PMC article.

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