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Page 1
Pulmonary primary oxysterol and bile acid synthesis as a predictor of outcomes in pulmonary arterial hypertension.
Alotaibi M, Harvey LD, Nichols WC, Pauciulo MW, Hemnes A, Long T, Watrous JD, Begzati A, Tuomilehto J, Havulinna AS, Niiranen TJ, Jousilahti P, Salomaa V, Bertero T, Kim NH, Desai AA, Malhotra A, Yuan JX, Cheng S, Chan SY, Jain M. Alotaibi M, et al. Among authors: bertero t. bioRxiv [Preprint]. 2024 Jan 23:2024.01.20.576474. doi: 10.1101/2024.01.20.576474. bioRxiv. 2024. PMID: 38328113 Free PMC article. Preprint.
Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension.
Harvey LD, Alotaibi M, Kim HJ, Tai YY, Tang Y, Sun W, El Khoury W, Woodcock CC, Aaraj YA, St Croix CM, Stolz DB, Lee J, Cheng MH, Schwantes-An TH, Desai AA, Pauciulo MW, Nichols WC, Webb A, Lafyatis R, Nouraie M, Wu H, McDonald JG, Chauvet C, Cheng S, Bahar I, Bertero T, Benza RL, Jain M, Chan SY. Harvey LD, et al. Among authors: bertero t. bioRxiv [Preprint]. 2024 Mar 1:2024.02.26.582142. doi: 10.1101/2024.02.26.582142. bioRxiv. 2024. PMID: 38464060 Free PMC article. Preprint.
Mechano-dependent sorbitol accumulation supports biomolecular condensate.
Torrino S, Oldham WM, Tejedor AR, Burgos IS, Rachedi N, Fraissard K, Chauvet C, Sbai C, O'Hara BP, Abélanet S, Brau F, Clavel S, Collepardo-Guevara R, Espinosa JR, Ben-Sahra I, Bertero T. Torrino S, et al. Among authors: bertero t. bioRxiv [Preprint]. 2023 Jul 25:2023.07.24.550444. doi: 10.1101/2023.07.24.550444. bioRxiv. 2023. Update in: Cell. 2024 Nov 16:S0092-8674(24)01271-6. doi: 10.1016/j.cell.2024.10.048 PMID: 37546967 Free PMC article. Updated. Preprint.
Mechano-dependent sorbitol accumulation supports biomolecular condensate.
Torrino S, Oldham WM, Tejedor AR, Burgos IS, Nasr L, Rachedi N, Fraissard K, Chauvet C, Sbai C, O'Hara BP, Abélanet S, Brau F, Favard C, Clavel S, Collepardo-Guevara R, Espinosa JR, Ben-Sahra I, Bertero T. Torrino S, et al. Among authors: bertero t. Cell. 2024 Nov 16:S0092-8674(24)01271-6. doi: 10.1016/j.cell.2024.10.048. Online ahead of print. Cell. 2024. PMID: 39591966
GLS2 links glutamine metabolism and atherosclerosis by remodeling artery walls.
Murcy F, Borowczyk C, Gourion-Arsiquaud S, Torrino S, Ouahrouche N, Barouillet T, Dussaud S, Couralet M, Vaillant N, Merlin J, Berquand A, Kaikkonen MU, McClelland RL, Tressel W, Stein J, Thorp EB, Bertero T, Barbry P, Bailly-Maitre B, Gautier EL, Karjalainen MK, Kettunen J, Duca L, Shea S, Yvan-Charvet L. Murcy F, et al. Among authors: bertero t. Nat Cardiovasc Res. 2024 Dec;3(12):1454-1467. doi: 10.1038/s44161-024-00566-1. Epub 2024 Nov 19. Nat Cardiovasc Res. 2024. PMID: 39562782
Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness.
Rachedi NS, Tang Y, Tai YY, Zhao J, Chauvet C, Grynblat J, Akoumia KKF, Estephan L, Torrino S, Sbai C, Ait-Mouffok A, Latoche JD, Al Aaraj Y, Brau F, Abélanet S, Clavel S, Zhang Y, Guillermier C, Kumar NVG, Tavakoli S, Mercier O, Risbano MG, Yao ZK, Yang G, Ouerfelli O, Lewis JS, Montani D, Humbert M, Steinhauser ML, Anderson CJ, Oldham WM, Perros F, Bertero T, Chan SY. Rachedi NS, et al. Among authors: bertero t. Cell Metab. 2024 Jun 4;36(6):1335-1350.e8. doi: 10.1016/j.cmet.2024.04.010. Epub 2024 May 2. Cell Metab. 2024. PMID: 38701775
Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension.
Tai YY, Yu Q, Tang Y, Sun W, Kelly NJ, Okawa S, Zhao J, Schwantes-An TH, Lacoux C, Torrino S, Al Aaraj Y, El Khoury W, Negi V, Liu M, Corey CG, Belmonte F, Vargas SO, Schwartz B, Bhat B, Chau BN, Karnes JH, Satoh T, Barndt RJ, Wu H, Parikh VN, Wang J, Zhang Y, McNamara D, Li G, Speyer G, Wang B, Shiva S, Kaufman B, Kim S, Gomez D, Mari B, Cho MH, Boueiz A, Pauciulo MW, Southgate L, Trembath RC, Sitbon O, Humbert M, Graf S, Morrell NW, Rhodes CJ, Wilkins MR, Nouraie M, Nichols WC, Desai AA, Bertero T, Chan SY. Tai YY, et al. Among authors: bertero t. Sci Transl Med. 2024 Jan 10;16(729):eadd2029. doi: 10.1126/scitranslmed.add2029. Epub 2024 Jan 10. Sci Transl Med. 2024. PMID: 38198571 Free PMC article.
Single Nucleotide Polymorphism rs9277336 Controls the Nuclear Alpha Actinin 4-Human Leukocyte Antigen-DPA1 Axis and Pulmonary Endothelial Pathophenotypes in Pulmonary Arterial Hypertension.
Hafeez N, Kirillova A, Yue Y, Rao RJ, Kelly NJ, El Khoury W, Al Aaraj Y, Tai YY, Handen A, Tang Y, Jiang D, Wu T, Zhang Y, McNamara D, Kudryashova TV, Goncharova EA, Goncharov D, Bertero T, Nouraie M, Li G, Sun W, Chan SY. Hafeez N, et al. Among authors: bertero t. J Am Heart Assoc. 2023 Apr 4;12(7):e027894. doi: 10.1161/JAHA.122.027894. Epub 2023 Mar 28. J Am Heart Assoc. 2023. PMID: 36974749 Free PMC article.
Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension.
Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, Chan SY. Bertero T, et al. J Clin Invest. 2022 May 16;132(10):e161077. doi: 10.1172/JCI161077. J Clin Invest. 2022. PMID: 35575096 Free PMC article. No abstract available.
60 results