Hwang SH - Search Results

1

GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.

Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter JF, Dror RO, Evers AS, Mukhopadhyay S, Manglik A. Hoppe N, et al. Among authors: hwang sh. Nat Struct Mol Biol. 2024 Apr;31(4):667-677. doi: 10.1038/s41594-024-01223-8. Epub 2024 Feb 7. Nat Struct Mol Biol. 2024. PMID: 38326651 Free PMC article.

2

G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning.

Hwang SH, Mukhopadhyay S. Hwang SH, et al. Birth Defects Res A Clin Mol Teratol. 2015 Jan;103(1):12-9. doi: 10.1002/bdra.23267. Epub 2014 Jun 11. Birth Defects Res A Clin Mol Teratol. 2015. PMID: 24917297

3

Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium.

Pal K, Hwang SH, Somatilaka B, Badgandi H, Jackson PK, DeFea K, Mukhopadhyay S. Pal K, et al. Among authors: hwang sh. J Cell Biol. 2016 Mar 28;212(7):861-75. doi: 10.1083/jcb.201506132. Epub 2016 Mar 21. J Cell Biol. 2016. PMID: 27002170 Free PMC article.

4

Trafficking to the primary cilium membrane.

Mukhopadhyay S, Badgandi HB, Hwang SH, Somatilaka B, Shimada IS, Pal K. Mukhopadhyay S, et al. Among authors: hwang sh. Mol Biol Cell. 2017 Jan 15;28(2):233-239. doi: 10.1091/mbc.E16-07-0505. Mol Biol Cell. 2017. PMID: 28082521 Free PMC article. Review.

5

Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.

Badgandi HB, Hwang SH, Shimada IS, Loriot E, Mukhopadhyay S. Badgandi HB, et al. Among authors: hwang sh. J Cell Biol. 2017 Mar 6;216(3):743-760. doi: 10.1083/jcb.201607095. Epub 2017 Feb 2. J Cell Biol. 2017. PMID: 28154160 Free PMC article.

6

The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner.

Hwang SH, White KA, Somatilaka BN, Shelton JM, Richardson JA, Mukhopadhyay S. Hwang SH, et al. Development. 2018 Jan 8;145(1):dev154054. doi: 10.1242/dev.154054. Development. 2018. PMID: 29222391 Free PMC article.

7

Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.

Shimada IS, Hwang SH, Somatilaka BN, Wang X, Skowron P, Kim J, Kim M, Shelton JM, Rajaram V, Xuan Z, Taylor MD, Mukhopadhyay S. Shimada IS, et al. Among authors: hwang sh. Cell Rep. 2018 Jan 30;22(5):1169-1184. doi: 10.1016/j.celrep.2018.01.018. Cell Rep. 2018. PMID: 29386106 Free PMC article.

8

Dominant negative GPR161 rare variants are risk factors of human spina bifida.

Kim SE, Lei Y, Hwang SH, Wlodarczyk BJ, Mukhopadhyay S, Shaw GM, Ross ME, Finnell RH. Kim SE, et al. Among authors: hwang sh. Hum Mol Genet. 2019 Jan 15;28(2):200-208. doi: 10.1093/hmg/ddy339. Hum Mol Genet. 2019. PMID: 30256984 Free PMC article.

9

Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia.

Hwang SH, Somatilaka BN, Badgandi H, Palicharla VR, Walker R, Shelton JM, Qian F, Mukhopadhyay S. Hwang SH, et al. Curr Biol. 2019 Mar 4;29(5):790-802.e5. doi: 10.1016/j.cub.2019.01.047. Epub 2019 Feb 21. Curr Biol. 2019. PMID: 30799239 Free PMC article.

10

Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities.

Shimada IS, Somatilaka BN, Hwang SH, Anderson AG, Shelton JM, Rajaram V, Konopka G, Mukhopadhyay S. Shimada IS, et al. Among authors: hwang sh. Dev Biol. 2019 Jun 1;450(1):47-62. doi: 10.1016/j.ydbio.2019.03.011. Epub 2019 Mar 23. Dev Biol. 2019. PMID: 30914320 Free PMC article.

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