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Mitochondrial defects and metabolic vulnerabilities in Lynch syndrome-associated MSH2-deficient endometrial cancer.
Bowen MB, Melendez B, Zhang Q, Moreno D, Peralta L, Chan WK, Jeter C, Tan L, Zal MA, Lorenzi PL, Dunner K, Yang RK, Broaddus RR, Celestino J, Gokul N, Whitley E, Schmandt R, Lu K, Kim HE, Yates MS. Bowen MB, et al. Among authors: lorenzi pl. bioRxiv [Preprint]. 2024 Jun 11:2024.06.10.596841. doi: 10.1101/2024.06.10.596841. bioRxiv. 2024. PMID: 38915709 Free PMC article. Preprint.
Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial metabolic reprogramming.
Wang Y, Kulkarni VV, Pantaleón García J, Leiva-Juárez MM, Goldblatt DL, Gulraiz F, Chen J, Donepudi SR, Lorenzi PL, Wang H, Wong LJ, Tuvim MJ, Evans SE. Wang Y, et al. Among authors: lorenzi pl. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524841. doi: 10.1101/2023.01.19.524841. bioRxiv. 2023. Update in: PLoS Pathog. 2023 Sep 11;19(9):e1011138. doi: 10.1371/journal.ppat.1011138. PMID: 36711510 Free PMC article. Updated. Preprint.
ATP-dependent citrate lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling of the Heart.
Liu S, Gammon ST, Tan L, Gao Y, Kim K, Williamson IK, Pham J, Davidian A, Khanna R, Gould BD, Salazar R, Vitrac H, Dinh A, Lien EC, de L Vitorino FN, Gongora JM, Martinez SA, Lawrence CSC, Kransdorf EP, Leffer D, Hanson B, Garcia BA, Vander Heiden MG, Lorenzi PL, Taegtmeyer H, Piwnica-Worms D, Martin JF, Karlstaedt A. Liu S, et al. Among authors: lorenzi pl. bioRxiv [Preprint]. 2024 Jun 21:2024.06.21.600099. doi: 10.1101/2024.06.21.600099. bioRxiv. 2024. PMID: 38948703 Free PMC article. Preprint.
Targeting DNA2 Overcomes Metabolic Reprogramming in Multiple Myeloma.
Thongon N, Ma F, Lockyer P, Baran N, Liu J, Jackson C, Rose A, Wildeman B, Marchesini M, Marchica V, Storti P, Giuliani N, Ganan-Gomez I, Adema V, Qing Y, Ha M, Fonseca R, Class C, Tan L, Kanagal-Shamanna R, Nolasco DB, Cerchione C, Montalban-Bravo G, Santoni A, Bueso-Ramos C, Konopleva M, Lorenzi P, Garcia-Manero G, Manasanch E, Viale A, Chesi M, Colla S. Thongon N, et al. bioRxiv [Preprint]. 2023 Feb 22:2023.02.22.529457. doi: 10.1101/2023.02.22.529457. bioRxiv. 2023. Update in: Nat Commun. 2024 Feb 8;15(1):1203. doi: 10.1038/s41467-024-45350-8. PMID: 36865225 Free PMC article. Updated. Preprint.
IL-1β-mediated inflammatory signaling drives ineffective erythropoiesis in early-stage myelodysplastic syndromes.
Adema V, Ganan-Gomez I, Ma F, Rodriguez-Sevilla JJ, Chien K, Yang H, Thongon N, Kanagal-Shamanna R, Loghavi S, Montalban-Bravo G, Hammond D, Gu Y, Tan R, Tan L, Lorenzi P, Al-Atrash G, Clise-Dwyer K, Bejar R, Pellegrini M, Garcia-Manero G, Colla S. Adema V, et al. bioRxiv [Preprint]. 2023 Sep 30:2023.09.28.560018. doi: 10.1101/2023.09.28.560018. bioRxiv. 2023. PMID: 37808770 Free PMC article. Preprint.
122 results