Haynes C - Search Results

1

Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells.

Ramalho T, Assis PA, Ojelabi O, Tan L, Carvalho B, Gardinassi L, Campos O, Lorenzi PL, Fitzgerald KA, Haynes C, Golenbock DT, Gazzinelli RT. Ramalho T, et al. Among authors: haynes c. Cell Metab. 2024 Mar 5;36(3):484-497.e6. doi: 10.1016/j.cmet.2024.01.008. Epub 2024 Feb 6. Cell Metab. 2024. PMID: 38325373 Free article.

2

Regulation of proteostasis and innate immunity via mitochondria-nuclear communication.

Kim S, Ramalho TR, Haynes CM. Kim S, et al. J Cell Biol. 2024 Mar 4;223(3):e202310005. doi: 10.1083/jcb.202310005. Epub 2024 Feb 9. J Cell Biol. 2024. PMID: 38335010 Free PMC article. Review.

3

Methods to analyze the mitochondrial unfolded protein response (UPR^mt).

Mallick A, Haynes CM. Mallick A, et al. Among authors: haynes cm. Methods Enzymol. 2024;707:543-564. doi: 10.1016/bs.mie.2024.07.029. Epub 2024 Aug 12. Methods Enzymol. 2024. PMID: 39488390

4

UPR^mt regulation and output: a stress response mediated by mitochondrial-nuclear communication.

Melber A, Haynes CM. Melber A, et al. Cell Res. 2018 Mar;28(3):281-295. doi: 10.1038/cr.2018.16. Epub 2018 Feb 9. Cell Res. 2018. PMID: 29424373 Free PMC article. Review.

5

LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria.

Yang Q, Liu P, Anderson NS, Shpilka T, Du Y, Naresh NU, Li R, Zhu LJ, Luk K, Lavelle J, Zeinert RD, Chien P, Wolfe SA, Haynes CM. Yang Q, et al. Nat Cell Biol. 2022 Feb;24(2):181-193. doi: 10.1038/s41556-021-00840-5. Epub 2022 Feb 14. Nat Cell Biol. 2022. PMID: 35165413 Free PMC article.

6

Vms1 Relieves a Mitochondrial Import Chokehold.

Lamech L, Haynes CM. Lamech L, et al. Dev Cell. 2017 Nov 6;43(3):259-260. doi: 10.1016/j.devcel.2017.10.022. Dev Cell. 2017. PMID: 29112848 Free article. Review.

7

The mitochondrial UPR: mechanisms, physiological functions and implications in ageing.

Shpilka T, Haynes CM. Shpilka T, et al. Nat Rev Mol Cell Biol. 2018 Feb;19(2):109-120. doi: 10.1038/nrm.2017.110. Epub 2017 Nov 22. Nat Rev Mol Cell Biol. 2018. PMID: 29165426 Review.

8

Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans.

Haroon S, Li A, Weinert JL, Fritsch C, Ericson NG, Alexander-Floyd J, Braeckman BP, Haynes CM, Bielas JH, Gidalevitz T, Vermulst M. Haroon S, et al. Among authors: haynes cm. Cell Rep. 2018 Mar 20;22(12):3115-3125. doi: 10.1016/j.celrep.2018.02.099. Cell Rep. 2018. PMID: 29562168 Free PMC article.

9

Folding the Mitochondrial UPR into the Integrated Stress Response.

Anderson NS, Haynes CM. Anderson NS, et al. Trends Cell Biol. 2020 Jun;30(6):428-439. doi: 10.1016/j.tcb.2020.03.001. Epub 2020 Apr 2. Trends Cell Biol. 2020. PMID: 32413314 Free PMC article. Review.

10

Mitochondrial translation, dynamics, and lysosomes combine to extend lifespan.

Ali L, Haynes CM. Ali L, et al. J Cell Biol. 2020 Jun 1;219(6):e202005084. doi: 10.1083/jcb.202005084. J Cell Biol. 2020. PMID: 32434220 Free PMC article.

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