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Page 1
A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells.
Della Volpe L, Midena F, Vacca R, Tavella T, Alessandrini L, Farina G, Brandas C, Lo Furno E, Giannetti K, Carsana E, Naldini MM, Barcella M, Ferrari S, Beretta S, Santoro A, Porcellini S, Varesi A, Gilioli D, Conti A, Merelli I, Gentner B, Villa A, Naldini L, Di Micco R. Della Volpe L, et al. Among authors: brandas c. Cell Rep Med. 2024 Nov 19;5(11):101823. doi: 10.1016/j.xcrm.2024.101823. Epub 2024 Nov 12. Cell Rep Med. 2024. PMID: 39536752 Free PMC article.
CD32 captures committed haemogenic endothelial cells during human embryonic development.
Scarfò R, Randolph LN, Abou Alezz M, El Khoury M, Gersch A, Li ZY, Luff SA, Tavosanis A, Ferrari Ramondo G, Valsoni S, Cascione S, Didelon E, Passerini L, Amodio G, Brandas C, Villa A, Gregori S, Merelli I, Freund JN, Sturgeon CM, Tavian M, Ditadi A. Scarfò R, et al. Among authors: brandas c. Nat Cell Biol. 2024 May;26(5):719-730. doi: 10.1038/s41556-024-01403-0. Epub 2024 Apr 9. Nat Cell Biol. 2024. PMID: 38594587 Free PMC article.
Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency.
Castiello MC, Brandas C, Ferrari S, Porcellini S, Sacchetti N, Canarutto D, Draghici E, Merelli I, Barcella M, Pelosi G, Vavassori V, Varesi A, Jacob A, Scala S, Basso Ricci L, Paulis M, Strina D, Di Verniere M, Sergi Sergi L, Serafini M, Holland SM, Bergerson JRE, De Ravin SS, Malech HL, Pala F, Bosticardo M, Brombin C, Cugnata F, Calzoni E, Crooks GM, Notarangelo LD, Genovese P, Naldini L, Villa A. Castiello MC, et al. Among authors: brandas c. Sci Transl Med. 2024 Feb 7;16(733):eadh8162. doi: 10.1126/scitranslmed.adh8162. Epub 2024 Feb 7. Sci Transl Med. 2024. PMID: 38324638 Free PMC article.
HyperIgE in hypomorphic recombination-activating gene defects.
Castiello MC, Brandas C, Capo V, Villa A. Castiello MC, et al. Among authors: brandas c. Curr Opin Immunol. 2023 Feb;80:102279. doi: 10.1016/j.coi.2022.102279. Epub 2022 Dec 16. Curr Opin Immunol. 2023. PMID: 36529093 Free article. Review.
A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing.
Angiolini F, Belloni E, Giordano M, Campioni M, Forneris F, Paronetto MP, Lupia M, Brandas C, Pradella D, Di Matteo A, Giampietro C, Jodice G, Luise C, Bertalot G, Freddi S, Malinverno M, Irimia M, Moulton JD, Summerton J, Chiapparino A, Ghilardi C, Giavazzi R, Nyqvist D, Gabellini D, Dejana E, Cavallaro U, Ghigna C. Angiolini F, et al. Among authors: brandas c. Elife. 2019 Mar 4;8:e44305. doi: 10.7554/eLife.44305. Elife. 2019. PMID: 30829570 Free PMC article.