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Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P. Zhao X, et al. Among authors: luo c. Cell Discov. 2024 Feb 6;10(1):14. doi: 10.1038/s41421-024-00648-1. Cell Discov. 2024. PMID: 38320990 Free PMC article.
Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility.
Chan JF, Zhang AJ, Yuan S, Poon VK, Chan CC, Lee AC, Chan WM, Fan Z, Tsoi HW, Wen L, Liang R, Cao J, Chen Y, Tang K, Luo C, Cai JP, Kok KH, Chu H, Chan KH, Sridhar S, Chen Z, Chen H, To KK, Yuen KY. Chan JF, et al. Among authors: luo c. Clin Infect Dis. 2020 Dec 3;71(9):2428-2446. doi: 10.1093/cid/ciaa325. Clin Infect Dis. 2020. PMID: 32215622 Free PMC article.
Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19).
Chan JF, Yuan S, Zhang AJ, Poon VK, Chan CC, Lee AC, Fan Z, Li C, Liang R, Cao J, Tang K, Luo C, Cheng VC, Cai JP, Chu H, Chan KH, To KK, Sridhar S, Yuen KY. Chan JF, et al. Among authors: luo c. Clin Infect Dis. 2020 Nov 19;71(16):2139-2149. doi: 10.1093/cid/ciaa644. Clin Infect Dis. 2020. PMID: 32472679 Free PMC article.
In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor.
Wen L, Tang K, Chik KK, Chan CC, Tsang JO, Liang R, Cao J, Huang Y, Luo C, Cai JP, Ye ZW, Yin F, Chu H, Jin DY, Yuen KY, Yuan S, Chan JF. Wen L, et al. Among authors: luo c. Int J Biol Sci. 2021 Apr 10;17(6):1555-1564. doi: 10.7150/ijbs.59191. eCollection 2021. Int J Biol Sci. 2021. PMID: 33907519 Free PMC article.
Low Environmental Temperature Exacerbates Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Golden Syrian Hamsters.
Chan JFW, Poon VKM, Chan CCS, Chik KKH, Tsang JOL, Zou Z, Chan CCY, Lee ACY, Li C, Liang R, Cao J, Tang K, Yuen TTT, Hu B, Huang X, Chai Y, Shuai H, Luo C, Cai JP, Chan KH, Sridhar S, Yin F, Kok KH, Chu H, Zhang AJ, Yuan S, Yuen KY. Chan JFW, et al. Among authors: luo c. Clin Infect Dis. 2022 Aug 24;75(1):e1101-e1111. doi: 10.1093/cid/ciab817. Clin Infect Dis. 2022. PMID: 34536277
SARS-CoV-2 exploits host DGAT and ADRP for efficient replication.
Yuan S, Yan B, Cao J, Ye ZW, Liang R, Tang K, Luo C, Cai J, Chu H, Chung TW, To KK, Hung IF, Jin DY, Chan JF, Yuen KY. Yuan S, et al. Among authors: luo c. Cell Discov. 2021 Oct 26;7(1):100. doi: 10.1038/s41421-021-00338-2. Cell Discov. 2021. PMID: 34702802 Free PMC article.
Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals.
Ye ZW, Ong CP, Tang K, Fan Y, Luo C, Zhou R, Luo P, Cheng Y, Gray VS, Wang P, Chu H, Chan JF, To KK, Chen H, Chen Z, Yuen KY, Ling GS, Yuan S, Jin DY. Ye ZW, et al. Among authors: luo c, luo p. Cell Mol Immunol. 2022 May;19(5):588-601. doi: 10.1038/s41423-022-00855-4. Epub 2022 Mar 29. Cell Mol Immunol. 2022. PMID: 35352010 Free PMC article.
Targeting papain-like protease for broad-spectrum coronavirus inhibition.
Yuan S, Gao X, Tang K, Cai JP, Hu M, Luo P, Wen L, Ye ZW, Luo C, Tsang JO, Chan CC, Huang Y, Cao J, Liang R, Qin Z, Qin B, Yin F, Chu H, Jin DY, Sun R, Chan JF, Cui S, Yuen KY. Yuan S, et al. Among authors: luo c, luo p. Protein Cell. 2022 Dec;13(12):940-953. doi: 10.1007/s13238-022-00909-3. Epub 2022 Apr 6. Protein Cell. 2022. PMID: 35384604 Free PMC article.
Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters.
Yuan S, Ye ZW, Liang R, Tang K, Zhang AJ, Lu G, Ong CP, Man Poon VK, Chan CC, Mok BW, Qin Z, Xie Y, Chu AW, Chan WM, Ip JD, Sun H, Tsang JO, Yuen TT, Chik KK, Chan CC, Cai JP, Luo C, Lu L, Yip CC, Chu H, To KK, Chen H, Jin DY, Yuen KY, Chan JF. Yuan S, et al. Among authors: luo c. Science. 2022 Jul 22;377(6604):428-433. doi: 10.1126/science.abn8939. Epub 2022 Jun 23. Science. 2022. PMID: 35737809 Free article.
Coronaviruses exploit a host cysteine-aspartic protease for replication.
Chu H, Hou Y, Yang D, Wen L, Shuai H, Yoon C, Shi J, Chai Y, Yuen TT, Hu B, Li C, Zhao X, Wang Y, Huang X, Lee KS, Luo C, Cai JP, Poon VK, Chan CC, Zhang AJ, Yuan S, Sit KY, Foo DC, Au WK, Wong KK, Zhou J, Kok KH, Jin DY, Chan JF, Yuen KY. Chu H, et al. Among authors: luo c. Nature. 2022 Sep;609(7928):785-792. doi: 10.1038/s41586-022-05148-4. Epub 2022 Aug 3. Nature. 2022. PMID: 35922005
8,521 results