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Page 1
H2S-Prdx4 axis mitigates Golgi stress to bolster tumor-reactive T cell immunotherapeutic response.
Oberholtzer N, Chakraborty P, Kassir MF, Dressman J, Das S, Mills S, Comte-Walters S, Gooz M, Choi S, Parikh RY, Hedley Z, Vaena S, DeMass R, Scurti G, Romeo M, Gangaraju VK, Berto S, Hill E, Ball LE, Mehta AS, Maldonado EN, Nishimura MI, Ogretmen B, Mehrotra S. Oberholtzer N, et al. Sci Adv. 2024 Nov 15;10(46):eadp1152. doi: 10.1126/sciadv.adp1152. Epub 2024 Nov 15. Sci Adv. 2024. PMID: 39546607 Free PMC article.
Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer.
Gedik ME, Saatci O, Oberholtzer N, Uner M, Akbulut O, Cetin M, Aras M, Ibis K, Caliskan B, Banoglu E, Wiemann S, Uner A, Aksoy S, Mehrotra S, Sahin O. Gedik ME, et al. Among authors: oberholtzer n. bioRxiv [Preprint]. 2023 Sep 14:2023.09.12.557273. doi: 10.1101/2023.09.12.557273. bioRxiv. 2023. Update in: Cancer Res. 2024 May 2;84(9):1475-1490. doi: 10.1158/0008-5472.CAN-23-2812 PMID: 37745348 Free PMC article. Updated. Preprint.
Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance.
Gao X, Wu Y, Chick JM, Abbott A, Jiang B, Wang DJ, Comte-Walters S, Johnson RH, Oberholtzer N, Nishimura MI, Gygi SP, Mehta A, Guttridge DC, Ball L, Mehrotra S, Sicinski P, Yu XZ, Wang H. Gao X, et al. Among authors: oberholtzer n. Cell Rep. 2023 Apr 25;42(4):112314. doi: 10.1016/j.celrep.2023.112314. Epub 2023 Mar 30. Cell Rep. 2023. PMID: 37000627 Free PMC article.
Eosinophils and melanoma: Implications for immunotherapy.
Robinson I, Santa Lucia G, Li A, Oberholtzer N, Plante J, Quinn KM, Reuben D, Mehrotra S, Valdebran M. Robinson I, et al. Among authors: oberholtzer n. Pigment Cell Melanoma Res. 2022 Mar;35(2):192-202. doi: 10.1111/pcmr.13025. Epub 2022 Jan 18. Pigment Cell Melanoma Res. 2022. PMID: 34927354 Free PMC article. Review.
Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels.
Senthivinayagam S, Serbulea V, Upchurch CM, Polanowska-Grabowska R, Mendu SK, Sahu S, Jayaguru P, Aylor KW, Chordia MD, Steinberg L, Oberholtzer N, Uchiyama S, Inada N, Lorenz UM, Harris TE, Keller SR, Meher AK, Kadl A, Desai BN, Kundu BK, Leitinger N. Senthivinayagam S, et al. Among authors: oberholtzer n. Mol Metab. 2021 Feb;44:101130. doi: 10.1016/j.molmet.2020.101130. Epub 2020 Nov 25. Mol Metab. 2021. PMID: 33248294 Free PMC article.
Pannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes.
Adamson SE, Meher AK, Chiu YH, Sandilos JK, Oberholtzer NP, Walker NN, Hargett SR, Seaman SA, Peirce-Cottler SM, Isakson BE, McNamara CA, Keller SR, Harris TE, Bayliss DA, Leitinger N. Adamson SE, et al. Among authors: oberholtzer np. Mol Metab. 2015 Jul 3;4(9):610-8. doi: 10.1016/j.molmet.2015.06.009. eCollection 2015 Sep. Mol Metab. 2015. PMID: 26413467 Free PMC article.