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Mechanistic patterns and clinical implications of oncogenic tyrosine kinase fusions in human cancers.
Chiarle R, Cheong TC, Jang A, Wang Q, Leonardi G, Ricciuti B, Alessi J, Federico AD, Awad M, Lehtinen M, Harris M. Chiarle R, et al. Res Sq [Preprint]. 2024 Jan 17:rs.3.rs-3782958. doi: 10.21203/rs.3.rs-3782958/v1. Res Sq. 2024. Update in: Nat Commun. 2024 Jun 14;15(1):5110. doi: 10.1038/s41467-024-49499-0 PMID: 38313284 Free PMC article. Updated. Preprint.
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
Ludwig LS, Lareau CA, Bao EL, Liu N, Utsugisawa T, Tseng AM, Myers SA, Verboon JM, Ulirsch JC, Luo W, Muus C, Fiorini C, Olive ME, Vockley CM, Munschauer M, Hunter A, Ogura H, Yamamoto T, Inada H, Nakagawa S, Ohzono S, Subramanian V, Chiarle R, Glader B, Carr SA, Aryee MJ, Kundaje A, Orkin SH, Regev A, McCavit TL, Kanno H, Sankaran VG. Ludwig LS, et al. Among authors: chiarle r. Blood. 2022 Apr 21;139(16):2534-2546. doi: 10.1182/blood.2021013753. Blood. 2022. PMID: 35030251 Free PMC article.
MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling.
Gonzalo P, Guadamillas MC, Hernández-Riquer MV, Pollán A, Grande-García A, Bartolomé RA, Vasanji A, Ambrogio C, Chiarle R, Teixidó J, Risteli J, Apte SS, del Pozo MA, Arroyo AG. Gonzalo P, et al. Among authors: chiarle r. Dev Cell. 2010 Jan 19;18(1):77-89. doi: 10.1016/j.devcel.2009.11.012. Dev Cell. 2010. PMID: 20152179 Free PMC article.
163 results