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A population pharmacokinetics model of balovaptan to support dose selection in adult and pediatric populations.
Schaedeli Stark F, Chavanne C, Derks M, Jolling K, Lagraauw HM, Lindbom L, Prins K, Silber Baumann HE. Schaedeli Stark F, et al. Among authors: silber baumann he. J Pharmacokinet Pharmacodyn. 2024 Jun;51(3):227-242. doi: 10.1007/s10928-023-09898-0. Epub 2024 Feb 3. J Pharmacokinet Pharmacodyn. 2024. PMID: 38308741 Free PMC article. Clinical Trial.
Development of a population pharmacokinetic model to characterize the pharmacokinetics of intrathecally administered tominersen in cerebrospinal fluid and plasma.
Yamamoto Y, Sanwald Ducray P, Björnsson M, Smart K, Grimsey P, Vatakuti S, Portron A, Massonnet B, Norris DA, Silber Baumann HE. Yamamoto Y, et al. Among authors: silber baumann he. CPT Pharmacometrics Syst Pharmacol. 2023 Sep;12(9):1213-1226. doi: 10.1002/psp4.13001. Epub 2023 Jun 13. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37221972 Free PMC article.
Estimation of FMO3 Ontogeny by Mechanistic Population Pharmacokinetic Modelling of Risdiplam and Its Impact on Drug-Drug Interactions in Children.
Cleary Y, Kletzl H, Grimsey P, Heinig K, Ogungbenro K, Silber Baumann HE, Frey N, Aarons L, Galetin A, Gertz M. Cleary Y, et al. Among authors: silber baumann he. Clin Pharmacokinet. 2023 Jun;62(6):891-904. doi: 10.1007/s40262-023-01241-7. Epub 2023 May 6. Clin Pharmacokinet. 2023. PMID: 37148485 Free PMC article.