Felsher DW - Search Results

1

Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma.

Deutzmann A, Sullivan DK, Dhanasekaran R, Li W, Chen X, Tong L, Mahauad-Fernandez WD, Bell J, Mosley A, Koehler AN, Li Y, Felsher DW. Deutzmann A, et al. Among authors: felsher dw. Nat Commun. 2024 Feb 1;15(1):963. doi: 10.1038/s41467-024-45128-y. Nat Commun. 2024. PMID: 38302473 Free PMC article.

2

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer.

Shachaf CM, Kopelman AM, Arvanitis C, Karlsson A, Beer S, Mandl S, Bachmann MH, Borowsky AD, Ruebner B, Cardiff RD, Yang Q, Bishop JM, Contag CH, Felsher DW. Shachaf CM, et al. Among authors: felsher dw. Nature. 2004 Oct 28;431(7012):1112-7. doi: 10.1038/nature03043. Epub 2004 Oct 10. Nature. 2004. PMID: 15475948 Free article.

3

Inactivation of MYC reverses tumorigenesis.

Li Y, Casey SC, Felsher DW. Li Y, et al. Among authors: felsher dw. J Intern Med. 2014 Jul;276(1):52-60. doi: 10.1111/joim.12237. J Intern Med. 2014. PMID: 24645771 Free PMC article. Review.

4

An essential role for the immune system in the mechanism of tumor regression following targeted oncogene inactivation.

Casey SC, Li Y, Felsher DW. Casey SC, et al. Among authors: felsher dw. Immunol Res. 2014 May;58(2-3):282-91. doi: 10.1007/s12026-014-8503-6. Immunol Res. 2014. PMID: 24791942 Free PMC article. Review.

5

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo.

Ye D, Shuhendler AJ, Cui L, Tong L, Tee SS, Tikhomirov G, Felsher DW, Rao J. Ye D, et al. Among authors: felsher dw. Nat Chem. 2014 Jun;6(6):519-26. doi: 10.1038/nchem.1920. Epub 2014 Apr 28. Nat Chem. 2014. PMID: 24848238 Free PMC article.

6

MYC activation is a hallmark of cancer initiation and maintenance.

Gabay M, Li Y, Felsher DW. Gabay M, et al. Among authors: felsher dw. Cold Spring Harb Perspect Med. 2014 Jun 2;4(6):a014241. doi: 10.1101/cshperspect.a014241. Cold Spring Harb Perspect Med. 2014. PMID: 24890832 Free PMC article. Review.

7

Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance.

Choi PS, Li Y, Felsher DW. Choi PS, et al. Among authors: felsher dw. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3316-24. doi: 10.1073/pnas.1406123111. Epub 2014 Jul 28. Proc Natl Acad Sci U S A. 2014. PMID: 25071175 Free PMC article.

8

Oncogene withdrawal engages the immune system to induce sustained cancer regression.

Casey SC, Li Y, Fan AC, Felsher DW. Casey SC, et al. Among authors: felsher dw. J Immunother Cancer. 2014 Jul 15;2:24. doi: 10.1186/2051-1426-2-24. eCollection 2014. J Immunother Cancer. 2014. PMID: 25089198 Free PMC article. Review.

9

MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state.

Li Y, Choi PS, Casey SC, Dill DL, Felsher DW. Li Y, et al. Among authors: felsher dw. Cancer Cell. 2014 Aug 11;26(2):262-72. doi: 10.1016/j.ccr.2014.06.014. Cancer Cell. 2014. PMID: 25117713 Free PMC article.

10

Activation of Cre recombinase alone can induce complete tumor regression.

Li Y, Choi PS, Casey SC, Felsher DW. Li Y, et al. Among authors: felsher dw. PLoS One. 2014 Sep 10;9(9):e107589. doi: 10.1371/journal.pone.0107589. eCollection 2014. PLoS One. 2014. PMID: 25208064 Free PMC article.

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